Dr. Kinane in pediatric pulmonologist who is an international expert in pediatric respiratory conditions.
- Centers & Specialties
- Clinical Interests
- Pulmonary disorders
- Bronchopulmonary dysplasia
- Interstitial lung disease
- Congenital pulmonary disease
- Exercise physiology (particularly exercise intolerance)
- Obstructive sleep apnea
- Respiratory disorders affecting sleep and exercise
- Primary ciliary dyskinesia
- Congenital central hypoventilation syndrome
- Medical Education
- MD, University College Dublin School of Medicine
- Residency, Children's Medical Center|Residency, Our Lady Hospital for Sick Children
- Fellowship, Massachusetts General Hospital
- Board Certifications
- Pediatric Pulmonology
- Sleep Medicine
- Boston: Massachusetts General Hospital
- Forestdale: Rehabilitation Hospital of the Cape and Islands
- Foxborough: Brigham and Women's/Mass General Health Care Center at Patriot Place
- Framingham: Lincoln Medical Center
- Patient Gateway
- Yes, learn more
- Insurances Accepted
- Aetna Health Inc.
- Beech Street
- Blue Cross Blue Shield - Blue Care 65
- Blue Cross Blue Shield - Indemnity
- Blue Cross Blue Shield - Managed Care
- Blue Cross Blue Shield - Partners Plus
- Cigna (PAL #'s)
- Fallon Community HealthCare
- Great-West Healthcare (formally One Health Plan)
- Harvard Pilgrim Health Plan - ACD
- Harvard Pilgrim Health Plan - PBO
- Health Care Value Management (HCVM)
- Humana/Choice Care PPO
- Medicare - ACD
- Neighborhood Health Plan - ACD
- Neighborhood Health Plan - PBO
- OSW - Connecticut
- OSW - Maine
- OSW - New Hampshire
- OSW - New York
- OSW - Rhode Island
- OSW - Vermont
- Private Health Care Systems (PHCS)
- Senior Whole Health
- Tufts Health Plan
- United Healthcare (non-HMO) - ACD
- United Healthcare (non-HMO) - PBO
- Patient Age Group
Dr. Kinane graduated from University College Dublin in 1983 with an MB. He completed Pediatric Residencies in Dublin (1987) and at the University of Texas South Western Medical School (1989). Following the completion of a Pediatric Pulmonary Fellowship at the Massachusetts General Hospital in 1992, he joined the faculty. He was appointed Chief of Pediatric Pulmonary (2000). In addition, he holds a number of leadership positions including Associate Chief for Education and Director of the Pediatric Sleep Program.
Since joining the faculty, Dr. Kinane has provided cutting edge clinical care to patients with a variety of pulmonary conditions including asthma, interstitial lung disease, sleep disorders, pneumonia, primary ciliary dyskinesia and pulmonary congenital abnormalities. He is seen as a International Expert on the genetic basis and treatment of interstitial lung disease, lung developmental abnormalities and the regulation of breathing.
His research focuses on the basic cause of interstitial lung disease and asthma. His sleep research focuses on the regulation of respiration and safe transportation of infants in car seats.
Dr. Kinane is also committed to the education of medical students, trainees and patients. He has won numerous teaching awards since joining the faculty. He has a particular focus on the use of social media to educate teenagers about a healthy lifestyle and asthma management.
- Research Summary
Dr. Kinane's research focuses on 3 distinct areas:
Regulation of cell migration:- Dr. Kinane's group focuses on transduction pathways that regulate cell migration and lung development. He has identified novel regulators of lung cell and inflammatory migration including Netrins. He found that these Netrin like molecules are critical in regulation of lung development and inflammatory responses. This research has broad implications for congenital lung malformation, blood vessel inflammation including coronary artery disease and autoimmune disease.
Regulation of the control of breathing:- In patients with central congenital hypoventilation syndrome, his group identified one of the molecular mechanisms of this syndrome. Recently he has extended this work to the regulation of breathing in common physiological conditions. He has recently focused his studies on airway obstruction in infants while placed in a car seat. This work has resulted in a number of highly cited manuscripts.
Pediatric interstitial lung disease:- Dr. Kinane's group works on the genetic basis, classification and treatment of interstitial disease. He has developed a genetics clinic in pulmonary to support this work.
- Kinane T.B. et al. Follicular bronchitis in the pediatric population. Chest. Oct. 1993 104(4) 1183-6.
- Kinane T.B. and Burton M.D. A genetic approach to the Congenital Central Hypoventilation Syndrome. PediatricPulmonology 1997; 23:133-5.
- Ly NP, Komatsuzaki K, Fraser IP, Tseng AA, Prodhan P, Moore KJ, and Kinane TB. Netrin-1 inhibits leukocyte migration in vitro and in vivo. Proc Natl Acad Sci U S A 2005; 102:14729-34.
- Cerar LK, Scirica CV, Stucin Gantar I, Osredkar D, Neubauer D, Kinane TB. A Comparison of Respiratory Patterns in Healthy Term Infants Placed in Car Safety Seats and Beds. Pediatrics. 2009 Sept 124(3):e396-402
- Kinane TB, Shailam R, Mark EJ., Case records of the Massachusetts General Hospital. 2011. A 9-month-old boy with recurrent tachypnea and respiratory distress N Engl J Med. 2011 Dec 8;365(23):2221-8.
Education is central to the mission of MassGeneral Hospital for Children. The education mission stretches the spectrum from medical students to residents to fellows to faculty. Indeed some of the techniques used to teach these medical learners are now used in pediatric patient education.
275 Cambridge Street
Boston MA, 02114
243 Charles Street
Boston MA, 02114-3002