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Thomas Bernard Kinane, MD

Chief, Pediatric Pulmonary Unit

Associate Chief for Education

Director of Pediatric Sleep Program and Pediatric Cardiopulmonary Exercise Laboratory

Dr. Kinane in pediatric pulmonologist who is an international expert in pediatric respiratory conditions.

  • Phone: 617-726-8707
Department of Pediatrics


  • MassGeneral Hospital for Children
  • Pulmonary
  • Sleep Disorders Program
  • Neuromuscular Service
  • Asthma
  • Cystic Fibrosis
Clinical Interests
Pulmonary disorders
Bronchopulmonary dysplasia
Interstitial lung disease
Congenital pulmonary disease
Exercise physiology (particularly exercise intolerance)
Obstructive sleep apnea
Respiratory disorders affecting sleep and exercise
Primary ciliary dyskinesia
Congenital central hypoventilation syndrome
Boston: Massachusetts General Hospital
Forestdale: Rehabilitation Hospital of the Cape and Islands
Foxborough: Brigham and Women's/Mass General Health Care Center at Patriot Place
Framingham: Lincoln Medical Center
Medical Education
MD, University College Dublin School of Medicine
Residency, Children's Medical Center
Residency, Our Lady Hospital for Sick Children
Fellowship, Massachusetts General Hospital
Board Certifications
Pediatric Pulmonology, American Board of Pediatrics
Sleep Medicine, American Board of Internal Medicine
Patient Gateway
Yes, learn more
Patient Age Group
Accepting New Patients
Accepting New Patients


Dr. Kinane graduated from University College Dublin in 1983 with an MB. He completed Pediatric Residencies in Dublin (1987) and at the University of Texas South Western Medical School (1989). Following the completion of a Pediatric Pulmonary Fellowship at the Massachusetts General Hospital in 1992, he joined the faculty. He was appointed Chief of Pediatric Pulmonary (2000).  In addition, he holds a number of leadership positions including Associate Chief for Education and Director of the Pediatric Sleep Program.

Since joining the faculty, Dr. Kinane has provided cutting edge clinical care to patients with a variety of pulmonary conditions including asthma, interstitial lung disease, sleep disorders, pneumonia, p
rimary ciliary dyskinesia and pulmonary congenital abnormalities. He is seen as a International Expert on the genetic basis and treatment of interstitial lung disease, lung developmental abnormalities and the regulation of breathing.

His research focuses on the basic cause of interstitial lung disease and asthma.  His sleep research focuses on the regulation of respiration and safe transportation of infants in car seats. 

Dr. Kinane is also committed to the education of medical students, trainees and patients.  He has won numerous teaching awards since joining the faculty.  He has a particular focus on the use of social media to educate teenagers about a healthy lifestyle and asthma management.


Dr. Kinane's research focuses on 3 distinct areas:

Regulation of cell migration:-
Dr. Kinane's group focuses on transduction pathways that regulate cell migration and lung development.  He has identified novel regulators of lung cell and inflammatory migration including Netrins. He found that these Netrin like molecules are critical in regulation of lung development and inflammatory responses. This research has broad implications for congenital lung malformation, blood vessel inflammation including coronary artery disease and autoimmune disease. 

Regulation of the control of breathing:-
In patients with central congenital hypoventilation syndrome, his group identified one of the molecular mechanisms of this syndrome. Recently he has extended this work to the regulation of breathing in common physiological conditions.  He has recently focused his studies on airway obstruction in infants while placed in a car seat. This work has resulted in a number of highly cited manuscripts. 

Pediatric interstitial lung disease:- Dr. Kinane's group works on the genetic basis, classification and treatment of interstitial disease. He has developed a genetics clinic in pulmonary to support this work.


  1. Kinane T.B. et al. Follicular bronchitis in the pediatric population. Chest.  Oct. 1993  104(4) 1183-6.
  2. Kinane T.B. and Burton M.D.  A genetic approach to the  Congenital Central Hypoventilation Syndrome.  PediatricPulmonology 1997; 23:133-5.   
  3. Ly NP, Komatsuzaki K, Fraser IP, Tseng AA, Prodhan P, Moore KJ, and Kinane TB. Netrin-1 inhibits leukocyte migration in vitro and in vivo. Proc Natl Acad Sci U S A 2005; 102:14729-34.
  4. Cerar LK, Scirica CV, Stucin Gantar I, Osredkar D, Neubauer D, Kinane TB. A Comparison of Respiratory Patterns in Healthy Term Infants Placed in Car Safety Seats and Beds. Pediatrics. 2009 Sept 124(3):e396-402
  5. Kinane TB, Shailam R, Mark EJ., Case records of the Massachusetts General Hospital. 2011. A 9-month-old boy with recurrent tachypnea and respiratory distress N Engl J Med. 2011 Dec 8;365(23):2221-8.

Medical Education for the Modern Student

Education is central to the mission of MassGeneral Hospital for Children. The education mission stretches the spectrum from medical students to residents to fellows to faculty. Indeed some of the techniques used to teach these medical learners are now used in pediatric patient education.

4th Annual Common Pediatric Hurdles: Advice and Updates from the Experts

New approaches to diagnosis and treatment of a number of problems encountered routinely in the office, including: child abuse and neglect; food allergies; pediatric pulmonary; pediatric orthopaedics; autism spectrum disorders; eating disorders; pediatric GERD.

Common Pediatric Hurdles: Advice and Updates from the Experts

Experts from the MassGeneral Hospital for Children will discuss commonly encountered issues in daily pediatric practice at this full-day live course in Dedham, MA.

Pediatric Pulmonary
275 Cambridge Street
POB 275
Boston, MA 02114

Phone: 617-726-8707
Fax: 617-724-2803

Pediatric Sleep Lab
243 Charles Street
Boston, MA 02114-3002

Phone: 617-573-5699
Fax: 617-573-5659

Pediatric Pulmonary
275 Cambridge Street
POB 275
Boston, MA 02114

Phone: 617-726-8707
Fax: 617-724-2803

Pediatric Sleep Lab
243 Charles Street
Boston, MA 02114-3002

Phone: 617-573-5699
Fax: 617-573-5659

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