Dr. Hoffmann is a cardiac radiologist with 15+ years of experience in magnetic resonance and computed tomography imaging research. His current focus is the value and accuracy of cardiac CT in an array of clinical applications.
- Clinical Interests
- Cardiac imaging
- Cardiac computed tomography (Cardiac CT)
- Medical Education
- MD, Leipzig Medical School
- Residency, Vienna General Hospital
- Boston: Massachusetts General Hospital
- Insurances Accepted
- Aetna Health Inc.
- Beech Street
- Blue Cross Blue Shield - Blue Care 65
- Blue Cross Blue Shield - Indemnity
- Blue Cross Blue Shield - Managed Care
- Blue Cross Blue Shield - Partners Plus
- Cigna (PAL #'s)
- Fallon Community HealthCare
- Great-West Healthcare (formally One Health Plan)
- Harvard Pilgrim Health Plan - PBO
- Health Care Value Management (HCVM)
- Humana/Choice Care PPO
- Medicare - ACD
- Neighborhood Health Plan - ACD
- Neighborhood Health Plan - PBO
- OSW - Maine
- OSW - New Hampshire
- OSW - Rhode Island
- Private Health Care Systems (PHCS)
- Railroad Medicare
- Senior Whole Health
- Tufts Health Plan
- United Healthcare (non-HMO) - ACD
- United Healthcare (non-HMO) - PBO
- Patient Age Group
Dr. Hoffmann is a radiologist with over 15 years of experience in noninvasive cardiovascular imaging. His past research interests related to a multidisciplinary research approach to systematically assess and validate the clinical utility of novel cardiovascular imaging technologies from bench to bedside. Over the last 15 years he has worked on the technical, analytical, clinical, epidemiological, and economic aspects of invasive and noninvasive imaging of atherosclerosis. One of the most daunting challenges has been to translate early technical progress in imaging into improvement of the clinical management of patients. The assessment and validation of biomarkers for clinical outcomes in cardiovascular imaging is still an important focus.
Dr. Hoffmann is a member of national initiatives, committees, and task forces for the RSNA, ACR, SCAI, AHA, and ACC, and serves as the director of several cardiovascular imaging courses. Dr Hoffmann, who has published >200 papers, reviews and book chapters, is Co-Chair of the Imaging Oversight Committee of the Framingham Heart Study, and an Associate Editor for Circulation Imaging and European Journal of Radiology. He is supported by a staff of 25 including MD radiologists/cardiologists, project managers, CT technologists, and IT staff/ programmers.
- Research Summary
My primary research interests relate to a multidisciplinary research approach to systematically assess and validate the clinical utility of novel cardiovascular imaging technologies from bench to bedside. Over the last 10 years I have worked on the technical, analytical, clinical, epidemiological, and economic aspects of invasive and noninvasive imaging of atherosclerosis. One of the most daunting challenges is to translate early technical progress in imaging into improvement of the clinical management of patients. I am studying the assessment and validation of cardiovascular imaging biomarkers for clinical outcomes within several large NIH-sponsored comparative effectiveness trials with >10000 patients.
- Hoffmann U, Bamberg F, Chae CU, Nichols JH, Rogers IS, Seneviratne SK, Truong QA, Cury RC, Abbara S, Shapiro MD, Moloo J, Butler J, Ferencik M, Lee H, Jang IK, Parry BA, Brown DF, Udelson JE, Achenbach S, Brady TJ, Nagurney JT. Coronary computed tomography angiography for early triage of patients with acute chest pain: the ROMICAT (Rule Out Myocardial Infarction using Computer Assisted Tomography) trial. J Am Coll Cardiol. 2009; 53(18):1642-50. PMID: 19406338
Hoffmann U, Moselewski F, Nieman K, Jang IK, Ferencik M, Rahman AM, Cury RC, Abbara S, Joneidi-Jafari H, Achenbach S, Brady TJ. Noninvasive assessment of plaque morphology and composition in culprit and stable lesions in acute coronary syndrome and stable lesions in stable angina by multidetector computed tomography. J Am Coll Cardiol. 2006; 47(8):1655-62. PMID: 16631006
Bamberg F, Truong QA, Blankstein R, Nasir K, Lee H, Rogers IS, Achenbach S, Brady TJ, Nagurney JT, Reiser MF, Hoffmann U. Usefulness of age and gender in the early triage of patients with acute chest pain having cardiac computed tomographic angiography. Am J Cardiol. 2009; 104(9):1165-70. PMID: 19840556
Mahabadi AA, Massaro JM, Rosito GA, Levy D, Murabito JM, Wolf PA, O'Donnell CJ, Fox CS, Hoffmann U. Association of pericardial fat, intrathoracic fat, and visceral abdominal fat with cardiovascular disease burden: the Framingham Heart Study. Eur Heart J. 2009; 30(7):850-6. PMID: 19136488
Hoffmann U, Massaro JM, Fox CS, Manders E, O'Donnell CJ. Defining normal distributions of coronary artery calcium in women and men (from the Framingham Heart Study). Am J Cardiol. 2008 Nov 1;102(9):1136-41. PMID: 18940279
The current guidelines for determining whether patients should begin taking statins to prevent cardiovascular disease are more accurate and more efficient than an earlier set of guidelines in assigning treatment to adults at increased risk for cardiovascular events and identifying those whose low risk rules out the need to take statins.
Incorporating coronary CT angiography into the initial evaluation of low-risk patients coming to hospital emergency departments with chest pain appears to reduce the time patients spend in the hospital without incurring additional costs or exposing patients to significant risks.
A large study to be published in the August issue of the American Journal of Medicine reports a record radiation dose reduction of 74.8% to MGH Cardiac CT patients during the past 6 years.
Using cardiac CT angiography can improve chest pain diagnoses without increased costs. Data presented by Udo Hoffmann, MD, MPH
Cardiac CT gives emergency physicians the ability to predict major adverse cardiac events (MACE) in patients presenting with chest pain, according to a study published in the May issue of the Journal of the American College of Cardiology.
55 Fruit Street
Boston MA, 02114-2696