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Jess L. Kaplan, MD

Assistant in Pediatrics

Jess L. Kaplan MD is a Pediatric Gastroenterologist at MassGeneral Hospital for Children. He specializes in the treatment of inflammatory bowel diseases (Crohn's Disease and Ulcerative Colitis) and general pediatric gastroenterology.

  • Phone: 617-726-8705
Department of Pediatrics


  • MassGeneral Hospital for Children
  • Gastroenterology & Nutrition
Clinical Interests
Inflammatory bowel disease
Crohn's disease
Ulcerative colitis
Eosinophilic gastrointestinal disease
Celiac disease
Boston: Massachusetts General Hospital
Forestdale: Rehabilitation Hospital of the Cape and Islands
Newton: Newton-Wellesley Hospital
Waltham: Mass General West
Medical Education
MD, University of Massachusetts Medical School
Residency, Massachusetts General Hospital
Fellowship, Massachusetts General Hospital
Board Certifications
Pediatrics, American Board of Pediatrics
Pediatric Gastroenterology, American Board of Pediatrics
Patient Gateway
Yes, learn more
Patient Age Group
Accepting New Patients
Accepting New Patients

Dr. Jess Kaplan is an attending physician in the Department of Pediatrics and Pediatric Gastroenterologist at MassGeneral Hospital for Children. He completed both his residency in pediatrics (2008) and fellowship in pediatric gastroenterology and nutrition (2011) at MassGeneral Hospital for Children.  Dr. Kaplan's clinical interests include the treatment of inflammatory bowel diseases (IBD) and other immune-mediated and general gastrointestinal disorders.  He sees patients in the Pediatric IBD Center at MGH and Newton Wellesley Hospital and in the IBD Transition clinic and performs clinical and translational research with a focus on the role of the gut microbiome in IBD as well as fecal microbiota transplantaiton.


View my most recent publications at PubMed

Koukos G, Polytarchou C, Kaplan JL, Morley-Fletcher A, Gras-Miralles B, Kokkotou E, Baril-Dore M, Pothoulakis C, Winter HS, Iliopoulos D. MicroRNA-124 Regulates STAT3 Expression and is Downregulated in Colon Tissues of Pediatric Patients with Ulcerative Colitis. Gastroenterology. 2013;145(4):842-853.

Kellermayer R, Mir SA, Nagy-Szakal D, Cox SB, Dowd SE, Kaplan JL, Sun Y, Reddy S, Bronsky J, Winter HS. Microbiota Separation and C-reactive protein elevation in Treatment Na?ve Pediatric Granulomatous Crohns Disease. J Pediatr Gastroenterol Nutr. 2012;55(3):243-250.

Su CW, Cao Y, Zhang M, Kaplan J, Su L, Fu Y, Walker WA, Xavier R, Cherayil BJ, Shi HN. Helminth Infection Impairs Autophagy-Mediated Killing of Bacterial Enteropathogens by Macrophages. J Immunol. 2012;189(3):1459-1466.

Kaplan JL, Walker WA. Early gut colonization and subsequent obesity risk. Curr Opin Clin Nutr Metab Care. 2012;15(3):278-284

Frontiers in Pediatrics Gastroenterology, Hepatology & Nutrition 2013

This course is designed to meet one or more of the following Accreditation Council of Graduate Medical Education competencies: Patient care; Medical knowledge; Practice-based learning and improvement; Interpersonal and communication skills; Professionalism; Systems-based practice

Pediatric Gastroenterology and Nutrition
55 Fruit Street
Boston, MA 02114-2696

Phone: 617-726-8705
Phone 2: 617-726-1450
Fax: 617-724-7011

Pediatric Gastroenterology and Nutrition
55 Fruit Street
Boston, MA 02114-2696

Phone: 617-726-8705
Phone 2: 617-726-1450
Fax: 617-724-7011

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