Mass General Department of Oral and Maxillofacial Surgery and the Center for Applied Clinical Investigation offer one-year and two-year post-doctoral fellowships in Clinical Investigation.  This unique curriculum leads to a Certificate from Mass General.  Candidates for the one-year track may pursue a concurrent Certificate from the Program in Clinical Effectiveness at the Harvard School of Public Health.  Two-year candidates may complete the fellowship in conjunction with an MPH or DPH program at the Harvard School of Public Health. 

The goal of the fellowship is to learn the principles and practice of patient-oriented research in preparation for an academic career as a clinical researcher in oral and maxillofacial surgery.  It is the intent that upon completion of this program, the Fellow will be able to:

  • Write effective grant proposals
  • Submit and defend IRB proposals
  • Design and implement scientifically sound patient-oriented research projects
  • Collect and analyze clinical data with scientific integrity
  • Write a clear and compelling manuscript of a patient-oriented research project
  • Practice as an effective clinical investigator and collaborator.

There is currently no institutional funding for this Fellowship. Candidates who are self- or institutionally-funded are welcome to apply.

Budget Considerations:

At this time, Mass General does not assess tuition or fees for this Fellowship program (subject to change) or for the courses of the Mass General Clinical Research Program.


Candidates for the Fellowship should be board-certified, board-eligible (or for international candidates, possess an equivalent recognizable certification) in oral and maxillofacial surgery. Fellows must be sponsored and supported by their home institution, including obtaining a letter of intent for ongoing employment in an academic position for a minimum period of two years upon completion of the Fellowship program. This program is designed for emerging residents and junior faculty who are committed to an ongoing academic career in clinical investigation in oral and maxillofacial surgery.

In some cases, the fellowship structure may be modified to fit the specific needs of an exceptional candidate or integrated with undergraduate dental training.  Candidates should be seeking a career path in academic oral and maxillofacial surgery.

Expected Outcomes

The Fellow will undergo periodic evaluation to assess compliance with minimum acceptable standards of performance in the progress of the key research program and the agreed upon academic curriculum.  In addition, the 2011-12 Fellow will meet the following milestones:

  • Complete application to HSPH Clinical Effectiveness Program or degree program
  • Complete with satisfactory performance a minimum of six (6) courses from the Mass General Clinical Research Program
  • Demonstrate proficiency in study design, data collection, and analysis as a key investigator on an Mass General-based research project
  • Submit an abstract based on research performed during the Fellowship to the IADR, AAOMS, a major national OMFS scientific meeting in the Fellow's home country, or other major scientific meeting with permission from the Fellowship Program Director
  • Submit at least one manuscript for publication based on research performed during the Fellowship
  • Write a proposal and complete data collection for a second project
  • Prepare a proposal for one future project that will be developed and refined during the Clinical Effectiveness Program and pursued after the Fellowship at the Fellow's home institution
  • Gain acceptance to and complete satisfactorily the chosen HSPH program


Didactic (classroom) work is a major component of the Fellowship in Clinical Investigation.  Through formal educational offerings, the Fellow will achieve a solid background in process and analytical methodology required to conduct sound scientific work.

The fellow may choose between two tracks: 1) one-year with Mass General certificate, or 2) two-year with Mass General certificate and HSPH degree.  In the case of Fellows choosing the two-year option, research projects may be expanded to run concurrently with the degree program.

In addition, Fellows may take advantage of course offerings from the Mass General Clinical Research Program.  These include (subject to change and availability):

  • Study design
  • Principles of ethical research
  • Biostatistics
  • Data management
  • Genetics for patient-oriented researchers
  • IRB issues
  • Tools for electronic data capture
  • Design and conduct of clinical trials
  • Grant writing
  • Scientific writing

Fellows will be expected to demonstrate satisfactory completion of all courses taken.

Clinical Experience

Opportunities for part-time clinical work are dependent upon the candidate's citizenship and licensing status.

Research Experience

The primary activity of the Fellow will be the participation in patient-oriented research, including taking a primary operational role in at least one major Mass General-based research project through the term of the Fellowship.  Topics for research projects vary from year to year.  The Fellow will be assigned a topic based on clinical interest, application to the home institution, and Mass General resources.  Current opportunities (subject to change) include potential work in the following clinical areas:

  • Outcomes of patients treated at Mass General for bisphosphonate-related osteonecrosis of the jaws
  • Outcomes following management of maxillofacial trauma as a risk factor for cervical spine injuries
  • Implants and implant survival
  • Medical management of giant cell tumors.

How to Apply

For more information on the CACI Fellowship, visit the Center for Applied Clinical Investigation.

Qualified applications should submit the following:

  • Letter of intent specifying the candidates interest in ongoing clinical research
  • Current CV indicating professional degrees, credentials, and experience
  • Letter of sponsorship from home institution indicating the degree of financial support and a commitment to a faculty position for a minimum of 2 years upon completion of the Fellowship
  • Two (2) additional letters of recommendation
  • A photocopy of your passport
  • Written verification of extramural funding or financial support.

Send all application materials to:
Center for Applied Clinical Investigation
Massachusetts General Hospital - Department of OMFS
55 Fruit Street - Warren 1201
Boston, MA  02114


  • Ya-wei Chen,  2014-2016
  • Firat Selvi, 2011-2012
  • Michael Markiewicz, 2006-2007
  • Seenu Susarla, 2004-2006
  • Sung Kiang Chuang, 2002-2004
  • Leslie Halpern, 2000-2002

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