Explore current research projects in the Endocrine Unit at Massachusetts General Hospital or search our open clinical trials and medical research studies.
Research in the Endocrine Unit focuses on metabolic bone diseases and mineral metabolism and ranges from trials of novel therapies for osteoporosis to use of genetically altered mice and cell biology to understand the factors that influence calcium and phosphate metabolism.
The Bastepe Laboratory investigates the role of the GNAS locus and its gene products in physiology and disease pathogenesis.
Our research focuses on inborn errors of phosphate metabolism and the endocrine regulation of phosphate homeostasis with an emphasis on the metabolic and homeostatic effects of phosphate.
The Demay Laboratory is focused on understanding the role of the vitamin D receptor (VDR) in skeletal maturation and in cutaneous homeostasis.
The Divieti-Pajevic Laboratory of the Massachusetts General Hospital Endocrine Unit investigates the complex interactions involved in bone metabolism.
The Kobayashi Laboratory investigates the genetics of skeletal development.
The Kronenberg laboratory uses genetically altered mice to study signaling by the PTH/PTHrP receptor in bone, bone development more generally and the relationships between cells of the osteoblast lineage and hematopoiesis.
Research in the Mannstadt Laboratory focuses on diseases of the parathyroid glands and mineral metabolism.
The Shimada Laboratory of the Massachusetts General Hospital Endocrine Unit investigates the complex interactions involved in bone development and remodeling.