Endocrine Unit

Bone Density Center

The Bone Density Center at Massachusetts General Hospital offers state-of-the-art testing for the diagnosis and follow-up of osteoporosis and other metabolic bone diseases.

Leading-edge Osteoporosis TreatmentPart of the Massachusetts General Hospital Endocrine Unit, the Bone Density Center provides leading-edge bone density testing services to help your primary care physician or specialist develop a treatment program tailored to your needs.

Osteoporosis is the most common cause of low bone mineral density. Bone density testing is very effective in diagnosing this condition, determining your risk for fractures and monitoring your response to therapy.

Early diagnosis of osteoporosis enables your doctor to begin proactive treatment to reduce your risk for fractures. Even if osteoporosis is diagnosed at a more advanced stage, you can still realize substantial benefits from treatment.
What to ExpectBased on your doctor’s referral, the Bone Density Center performs one of several tests to determine the causes of your symptoms and provide your primary care physician or specialist with information to help develop a treatment plan.

The standard test for men, women and children measures bone density of the spine and hip. In certain cases, we may also run tests to identify any fractures in your spine or to measure the bone density of your forearm or whole body.

All of our tests use dual-energy X-ray absorptiometry (DXA), making for a pain-free process that uses very low doses of radiation and lasts only about 10 minutes.

Most medical insurance companies cover bone density testing for patients with certain medical conditions, though many insurers limit the frequency of these tests.
Understanding Your ResultsOur standard reports include measurement of your bone density and how it has changed over time. Your results are compared with the normal range for:

  • People who are the same age, gender and ethnicity as you (your Z-score)
  • Healthy young adults who are the same gender and ethnicity as you (your T-score)

Your bone density reports are available to your doctor within 48 hours and include general recommendations for medical management.

If your bone density is normal, you won't need further testing for years. If your bone density is low or you have had a fracture, you may benefit from medical treatment and/or future monitoring with bone density tests.

Most forms of osteoporosis can be treated by your primary care physician. If you have a complex case, your doctor may refer you to Mass General Endocrine and Osteoporosis Associates for specialized care.

Leaders in the Field Founded in 1976, the Massachusetts General Hospital Bone Density Center was the first center of its kind in the eastern United States. The Bone Density Center played an important role in the development of dual-energy X-ray absorptiometry (DXA), the current standard for measuring bone mineral density. DXA allows physicians to diagnose osteoporosis and related bone diseases early, often before you suffer a fracture.

DXA is also an important tool for researching and developing new osteoporosis treatments. Using DXA, our physicians and researchers can determine the effectiveness of specific treatments in groups of patients and in individuals. This capability has accelerated the development and application of improved methods to treat osteoporosis.

Mass General was the first hospital to employ DXA in a clinical setting and in osteoporosis research. Robert Neer, MD, Bone Density Center founder and director, wrote the first paper describing the use of DXA in humans. He also coined the term "T-score" to describe the density of an adult's bones compared with that of the average young adult of the same gender and ethnicity. This score serves as a rough indicator of the need for osteoporosis treatment.
The Latest Diagnostic Technology

Our diagnostic technology includes:

  • Lower-spine mineral density (in both front-to-back and side views)
  • Hip mineral density (in the femoral neck and total hip)
  • Forearm mineral density
  • Whole-body bone mineral density

Recently, we added a new technique called vertebral fracture analysis (VFA). This test of the lower and upper spine can detect the presence of a fracture. If you have a vertebral fracture you have much higher risk of having another fracture in the next three to five years.

In addition, we are one of the few programs in the United States using a dedicated, high-resolution CT scanner for research measurements of bone density and bone structure. This equipment produces images down to the microscopic level—and appears to provide even better diagnostic information than DXA technology. While the scanner is currently used for experimental purposes only, it may one day become the standard for bone density testing.
Balancing Clinical Care and Research We often recruit for clinical trials that offer access to new and promising therapies. Search for open clinical trials

The same endocrinologists who analyze and interpret our patients' bone density tests also conduct osteoporosis research and have successfully competed for external research-support funds.

Training the Next GenerationAs part of an academic medical center, our physicians are committed to training the next generation of endocrinologists and osteoporosis experts. Through the Endocrinology Fellowship Program, we help to prepare physicians for careers in clinical and academic medicine.Our Staff

DoctorsSheri-Ann Burnett-Bowie, MD, MPH
Joel Finkelstein, MD
Benjamin Leder, MD
Robert Neer, MD
Elaine Yu, MD
TechniciansRobbin Cleary
Karen Barbarisi
Sheila Gnerre
Sarah Zhang
Patient AssistantsNancy McKie
Diane Puopolo

Osteoporosis

Osteoporosis, or porous bone, is a disease in which there is a loss of bone mass and destruction of bone tissue, causing weakening of the bones in the hips, spine and wrists.

The following related clinical trials and research studies are currently seeking participants at Massachusetts General Hospital. Search for clinical trials and studies in another area of interest.

Bone Density Center

Emerson Place
10 Emerson Place, Suite 1
Boston, MA 02114

Phone: 617-726-3839
Fax: 617-724-0696
Hours: 8:30 am - 4:00 pm

Disabled Access: yes

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