IVF/ART Program

IVF/ART Program

The Massachusetts General Hospital Fertility Center's IVF/ART Program offers leading-edge assisted reproductive technology (ART) services, including in vitro fertilization (IVF) and single-embryo transfer, in a highly individualized, private setting.

About this Program

At the Massachusetts General Hospital Fertility Center, our experienced physicians strive to achieve the highest and safest pregnancy rates. We tailor our approach to best suit the needs of each individual patient.

Our offices provide a quiet, private setting for many ART treatments, such as:

  • IVF
  • Single-embryo transfer
  • Intrauterine insemination (IUI)
  • Intracytoplasmic sperm induction (ICSI)
  • Assisted embryo hatching
  • Embryo cryopreservation
  • Egg freezing/banking
  • Preimplantation genetic diagnosis (PGD)
  • Sperm donation
  • Egg donation
  • Surrogacy

Highly Specialized Expertise

Since its founding in 1992, the IVF/ART Program has been directed by Thomas L. Toth, MD. He is a member of the Society for Assisted Reproductive Technology and the American Society of Reproductive Medicine.

In addition to Dr. Toth, the Fertility Center includes a team of professionals with specialized expertise in treating a variety of conditions:

Preparing Future Leaders in the Field

The Reproductive Endocrinology and Infertility Fellowship prepares future leaders in our field. In this highly competitive fellowship program, fellows work side by side with our physicians and scientists, contributing to important advances in clinical care and fertility research.

For more information on our fellowship program, please call 617-726-6942.

What to Expect

Safety is our number one priority. Massachusetts General Hospital Fertility Center clinicians reduce the risks associated with multiple gestations by using techniques such as:

  • Embryo cryopreservation (freezing and preserving human embryos)
  • Single-embryo transfer (transferring one rather than multiple fertilized embryos to the uterus)

In short, we strive to do more with less.

We are also among the few fertility centers in the country to routinely offer elective single-embryo transfer to women under age 35.

What to Expect

Our offices offer patients unsurpassed privacy. We deliver all in vitro fertilization (IVF) and assisted reproductive technology (ART) services in one self-contained suite located on the 10th floor of the Yawkey Building for Outpatient Care, overlooking Beacon Hill. When necessary, we work closely with other Mass General specialists—including urologists, embryologists and obstetricians/gynecologists—providing the highest level of care for patients.

Most patients are referred to the IVF/ART Program by their obstetrician/gynecologist or primary care physician. At your first appointment, we will review your medical history, discuss the most appropriate options to help you achieve pregnancy and develop your personalized treatment plan.

Throughout treatment, our patients enjoy a personal relationship with the physician in charge of their care as well as the other Fertility Center physicians on their team. A physician, rather than a technician, performs all ultrasound exams at our facility—another example of the personal involvement we believe makes for the best results.

Our embryology lab performs embryo transfers on the second, third or fifth day of embryo development to maximize success of individual patients.

Support If You Need It

We typically offer several possible treatment approaches for each patient. Ultimately, you are responsible for choosing the one that best suits your preferences. But should you struggle in reaching a decision, we offer support through Mass General social workers, financial services personnel, support groups or clergy.

Advancing Basic Science

In addition to working with patients, our physician-scientists are at the forefront of clinical research. For instance, we are conducting ongoing research into better options in egg preservation. We believe this research has exciting potential and hope it will bring new options for safely prolonging fertility in patients around the world.

The center also is working with the Harvard School of Public Health on an ongoing NIH study that is analyzing the effect of the environment on fertility. For information on participating in this program, please call 617-726-8868.

Conditions & Diseases

  • Infertility

    Infertility is defined by the American Society for Reproductive Medicine (ASRM) as a disease of the reproductive system that impairs the body's ability to perform the basic function of reproduction.

  • Pregnancy

    A pregnancy is divided into three phases, called trimesters. Each trimester has its own significant milestones.

  • Symptoms and Diagnosis of Multiple Pregnancy

    Symptoms of multiple pregnancy may include: uterus is larger than expected for the dates in pregnancy, increased morning sickness, increased appetite, excessive weight gain - especially in early pregnancy, or fetal movements felt in different parts of abdomen at same time.


Contact Us

Fertility Center

Yawkey Center for Outpatient Care

32 Fruit StreetSuite 10A Boston, MA 02114
  • Phone: 617-726-8868
  • Fax: 617-724-8882

Other Locations

Mass General/North Shore Center for Outpatient Care
104 Endicott Street, Suite 304
Danvers, MA 01923

Phone: 978-882-6767
Specialist voicemail: 978-825-6221
Fax: 978-882-6775


  • Two decades of transforming families - 10/5/2012, Mass General

    Families helped by the MGH Vincent Obstetrics & Gynecology Fertility Clinic gathered Sept. 22 in the Bulfinch Tents to celebrate the 20th anniversary of the In Vitro Fertilization (IVF) Unit.


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