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Daniel Stephan Pratt, MD

Clinical Director, Liver Transplantation

Director, Autoimmune & Cholestatic Liver Center

  • Phone: 617-726-3313
Department of Medicine


  • Cancer Center
  • Gastrointestinal Cancers
  • Digestive Healthcare Center
  • Liver Center
  • Colorectal Center
  • Transplant Center
  • Liver Transplant
Clinical Interests
Primary Biliary Cirrhosis
Primary sclerosing cholangitis
Autoimmune hepatitis, Autoimmune liver disease
Hepatitis B
Hepatitis C
Hepatocellular carcinoma
Abnormal liver function tests
Liver tumors
Boston: Massachusetts General Hospital
Danvers: The Mass General/North Shore Center for Outpatient Care
Medical Education
MD, Johns Hopkins University School of Medicine
Residency, Tufts Medical Center
Fellowship, Tufts Medical Center
Board Certifications
Gastroenterology, American Board of Internal Medicine
Patient Age Group
Accepting New Patients
Accepting New Patients


Daniel S. Pratt, MD is an Assistant Professor of Medicine at Harvard Medical School, Clinical Director of Liver Transplantation, and Director of the Autoimmune and Cholestatic Liver Center at the Massachusetts General Hospital.

Dr. Pratt received his B.A. from Bowdoin College and his M.D. from the Johns Hopkins University School of Medicine.  He completed a residency in Internal Medicine and a fellowship in Gastroenterology and Hepatology at the Tufts-New England Medical Center.  He served on the faculty of the Tufts University School of Medicine from 1995 until 2004.  Dr. Pratt was the Medical Director of the Liver Transplant Program and Clinical Chief of the Division of Gastroenterology at the Tufts Medical Center. He joined the faculty of the Harvard Medical School and the MGH Gastrointestinal Unit in 2004.

Dr. Pratt's particular area of clinical interest is autoimmune and cholestatic liver disease including autoimmune hepatitis, primary biliary cirrhosis, primary sclerosing cholangitis, and IgG4 associated liver disease.  He also does work in cholangiocarcinoma, hepatocellular carcinoma, viral hepatitis, and cirrhosis/endstage liver disease. Dr. Pratt is the head of the PSC Registry at MGH. 

Dr. Pratt has written extensively on liver disease and has been the recipient of numerous teaching awards.

ResearchPrincipal Investigator, PSC Registry at MGH


View my most recent publications at PubMed

Pratt DS. Liver Chemistry and Function Tests. In Feldman M, et al, editors. Sleisenger and Fordtran's Gastrointestinal and Liver Disease, 9th Edition, 2010.

Pratt DS. Primary Biliary Cirrhosis. In Greenberger N, et al, editors. Current Diagnosis and Treatment in Gastroenterology, Hepatology, and Endoscopy, 2009.

In General 03.04.11

In General Awards and Honors

Gastroenterology Associates
55 Fruit Street
Boston, MA 02114-2696

Phone: 617-726-3313
Fax: 617-724-6832

Mass General/North Shore Center for Outpatient Care
102 Endicott Street
Danvers, MA 01923-3623