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James Louis (Jim) Januzzi, Jr., MD

Roman W. DeSanctis Endowed Distinguished Clinical Scholar in Medicine

Director, Dennis and Marilyn Barry Fellowship in Cardiology Research

  • Phone: 617-724-6750
Department of Medicine


  • Critical Care Center
  • Heart Center
  • Heart Valve Program
  • Non-invasive Cardiology
  • Thoracic Aortic Center
  • General Clinical Cardiology
  • Cardiovascular Performance Program
  • Coronary Artery Disease Program
  • Echocardiography
  • Vascular Center
  • Cardiology/Vascular Medicine
Clinical Interests
Heart failure
Acute coronary syndromes
Aortic disease
Acute aortic dissection
Coronary artery disease
Valvular heart disease
Boston: Massachusetts General Hospital
Medical Education
MD, New York Medical College
Residency, Brigham and Women's Hospital
Fellowship, Massachusetts General Hospital
Board Certifications
Cardiovascular Disease, American Board of Internal Medicine
Foreign Languages
Patient Age Group
Accepting New Patients
Not Accepting New Patients

BiographyDr. Januzzi has been a member of the Massachusetts General Hospital Cardiology Division since 2000 where he is the Roman W. DeSanctis Endowed Distinguished Clinical Scholar in Medicine.  He is also the Hutter Family Professor of Medicine at Harvard Medical School and is on faculty at the Harvard Clinical Research Institute.

Dr. Januzzi graduated first in his class from New York Medical College in 1994, and subsequently did a residency in Internal Medicine at the Brigham and Women's Hospital, followed by a cardiology and echocardiography fellowship at Massachusetts General Hospital.  Since joining the staff at MGH, Dr. Januzzi is an active clinician, with a focus on acute myocardial infarction, chronic coronary artery disease, acute heart failure, chronic heart failure, and aortic disease.  He is an active teacher, and has a busy research program, with a specific focus on cardiac biomarker testing.  He has published more than 400 manuscripts, and has edited 3 textbooks, and speaks widely on the topic of biomarker testing in heart disease.  He has served as the Cardiology Consultant to the Boston Red Sox since 2005.


Dr. Januzzi has an active, world-recognized program in cardiac biomarker testing.  His main area of interest focuses on the use of biomarkers to better recognize, risk stratify, and manage cardiovascular disease.  He has done pioneering work on several novel tests now widely available for clinical use.


View my most recent publications at PubMed

Dr. Januzzi has published more than 300 peer reviewed publications, more than 100 review articles and book chapters and has edited three text books.

Scholar program established

At age 81, Roman W. DeSanctis, MD, is one of the hospital’s most veteran and most beloved physicians. To honor the legendary MGH cardiologist, the Roman W. DeSanctis, MD, Endowed Distinguished Scholar in Medicine has been established through the generosity of donor Joan Fu and several others.

Safe passage

It was a perfect slide into second base. Keith Harris was safe – but a small abrasion on his left leg would prove otherwise.

Januzzi first incumbent of Hutter Family Professorship

James Januzzi, MD, director of the MGH Cardiac Intensive Care Unit, was honored Sept. 8 in a ceremony at Harvard Medical School (HMS) as the first incumbent of the Hutter Family Professorship in Medicine in the Field of Cardiology.

Cardiac biomarker levels strongly predict outcome of bypass surgery

Levels of a biomarker used in the diagnosis of heart attacks are almost universally elevated in patients who have undergone coronary-artery bypass grafting (CABG) and, when markedly elevated, powerfully predict the risk of complications.

Biomarker-guided heart failure treatment significantly reduces complications

Adding regular testing for blood levels of a biomarker of cardiac distress to standard care for the most common form of heart failure may significantly reduce the incidence of cardiovascular complications, a new MGH study finds.

Cardiac Unit Associates
55 Fruit Street
Boston, MA 02114-2696

Phone: 617-724-6750
Phone 2: 617-726-3443
Fax: 617-643-1620

Cardiac Unit Associates
55 Fruit Street
Boston, MA 02114-2696

Phone: 617-724-6750
Phone 2: 617-726-3443
Fax: 617-643-1620

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Request an appointment at the Corrigan Minehan Heart Center

Call the Massachusetts General Hospital Corrigan Minehan Heart Center outpatient access nurse at 866-644-8910