Patients who have severe aortic stenosis (a narrowing of the valve that restricts blood flow) and are considered high risk or non-operable for open-chest surgery are candidates for the percutaneous aortic valve replacement procedure.

About The Procedure

During this procedure, physicians use minimally invasive techniques to implant a new heart valve without open-heart surgery. Physicians use a transfemoral (from the leg) or transapical (through the chest) approach, by inserting a transcatheter heart valve that is mounted and crimped onto a balloon delivery catheter. It is then threaded through the patient’s circulatory system and directly into the heart’s pumping chamber.

Upon reaching the site of the patient’s diseased heart valve, the balloon expands, and the transcatheter heart valve is deployed across the patient’s diseased valve. This procedure is performed on a beating heart, meaning that there is no need for a cardiopulmonary bypass and its associated risks.


Advancements in transcatheter technologies hold promise for a large number of high-risk patients suffering from severe aortic stenosis, including older patients or patients suffering from additional conditions. This new type of a procedure has the potential to treat and heal many of these patients who are ineligible for traditional open-heart surgery.

Inclusion and Exclusion Criteria

Learn about the criteria needed to refer a patient to the PARTNER Trial at Mass General Hospital:

Back to Top