LDL Apheresis

LDL apheresis is a dialysis-like therapy that reduces LDL cholesterol levels by as much as 60 to 70 percent in patients with severely high cholesterol.

About This Procedure

Certain patients with very high, poorly controlled, LDL cholesterol levels can receive LDL apheresis at the Massachusetts General Hospital Corrigan Minehan Heart Center. A dialysis-like therapy, this treatment is performed bi-weekly and reduces LDL cholesterol levels by 60 to 70 percent.

LDL apheresis is a dialysis-like therapy in that the patient’s blood is passed through a machine to remove the LDL. Two veins must be accessed to do this. Patients visit Mass General Hospital bi-weekly to receive the treatment. These two to four hour treatments are generally very well tolerated by patients and reduce LDL levels, improving the standard of living for many patients.

Qualifying Patients

  • An LDL above 300 mg/dL in the absence of coronary disease or
  • An LDL above 200 mg/dL with coronary disease


Contact Us

Corrigan Minehan Heart Center

55 Fruit Street Boston, MA 02114
  • Near Public Transit
  • Handicapped Accessible
  • Phone: 866-644-8910

If you are a new patient, you may call the Corrigan Minehan Heart Center outpatient access office at 866-MGH-8910, or complete our online appointment form to request an appointment. A member of our access team will ask you more about your condition and symptoms, and match you with the best-fitting Corrigan Minehan Heart Center physician.

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