Resynchronization and Advanced Cardiac Therapeutics Program

Resynchronization & Advanced Cardiac Therapeutics

The Resynchronization and Advanced Cardiac Therapeutics Program at the Massachusetts General Hospital Corrigan Minehan Heart Center offers cardiac resynchronization therapy, or the use of a specialized pacemaker to treat patients with heart failure.
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Call to request an appointment or referral 866-644-8910


Physicians within theResynchronization and Advanced Cardiac Therapeutics Programtreat patients with heart failure who have diminished heart function and need special pacemaker therapy to synchronize the pumping action of the heart.

This program works through the collaborative efforts of the Heart Failure and Cardiac Transplant Program, Cardiac Arrhythmia Service and echocardiography services at the Massachusetts General Hospital Corrigan Minehan Heart Center. We also work closely with referring primary cardiologists or internists to ensure continuity of care for patients.

Coordinating the Beating of the Heart

Cardiac resynchronization therapy is provided for patients with heart failure due to an abnormality in the pumping of the heart's ventricles. The heart's ventricles are supposed to contract simultaneously, but in many patients with heart failure, they may beat out of synchrony. Learn about cardiac resynchronization therapy

Care within theResynchronization and Advanced Cardiac Therapeutics Programtruly has no boundaries. Our specialists care for patients in inpatient, outpatient and emergency room settings, as well as follow them remotely in their homes. Bluetooth and radiofrequency (RF) capabilities are typically used in coordination with defibrillator and cardiac resynchronization therapy.

Benefits of Cardiac Resynchronization Therapy

Our physicians have found that cardiac resynchronization therapy can offer patients a number of benefits. Some of these benefits include:

  • Improved quality of life
  • Increased exercise capacity
  • Reduction in hospitalization for heart failure
  • Reduction in mortality rates

Cardiac resynchronization therapy involves the placement of an implantable biventricular pacing device with three leads (right atrial, right ventricular and left ventricular) that synchronize ventricular contractions. The result is a more efficient heart, and more importantly, a better quality of life for our patients.

This proactive approach saves lives by alerting patients and physicians often before symptoms occur. They receive detailed information on how the heart is beating and can call a patient into the hospital if there is a medical emergency.

Treatments and Procedures

Most patients are seen for three to four visits to maximize treatment therapies. Our specialists offer a variety of treatments and procedures including:

  • An evaluation of cardiac resynchronization therapy candidates by specialists in heart failure, electrophysiology and echocardiography
  • Cardiac resynchronization therapy device implantation
  • A post-implant evaluation by a team of doctors and nurses, designed to individualize treatment strategies for our patients
  • Patient education
  • Device interrogations
  • Echocardiography-guided device optimization and follow-up care
  • Home or remote-monitoring and follow-up care
  • Opportunities for patients to participate in cutting-edge treatment strategies

About this Program

The Resynchronization and Advanced Cardiac Therapeutics Program was established in November of 2005 to provide multidisciplinary care to heart failure patients eligible for device therapy. Care is provided through the collaborative effort and expertise of echocardiography, electrophysiology and heart failure specialists. The program uses research and evidence-based medicine to provide cutting-edge treatment options to patients.

AllResynchronization and Advanced Cardiac Therapeutics Program physicians are on the faculty of Harvard Medical School, which means they not only have a mission to provide the best possible patient care, but also a commitment to educate the next generation of medical professionals.

Our Vision

Some of the important objectives of the program are to:

  • Enhance the extent of benefit that patients receive from cardiac resynchronization therapy
  • Provide integrated and multidisciplinary care to enhance and improve clinical outcomes
  • Identify patients who might not show adequate responses in a timely fashion and prevent an exacerbation of their heart failure
  • Provide remote monitoring of devices, which enable early intervention and prevent hospitalizations

Our goal is to deliver state-of-the-art device therapy to improve the quality of life of our patients

Learn about cardiac resynchronization therapy

A Leader in Research

Specialists within the  Resynchronization and Advanced Cardiac Therapeutics Program have a significant role in several national and international multicenter studies. We have advanced the field of device therapy by:

  • Improving patient selection and predicting response to cardiac resynchronization therapy. Our work has led to the creation of a novel response score to predict clinical outcomes in this patient group
  • Advancing and developing novel ventricular lead implantation strategies. We have used novel rotational venography and imaging techniques to propose and substantiate new coronary venous anatomy classification and to redefine the best views for lead implantation
  • Developing novel image integration strategies for cardiac resynchronization therapy. Our physicians have done innovative work integrating computed tomography, ultrasound and fluoroscopy to create better clinical strategies to facilitate device implantation and patient follow up
  • Using device diagnostics and remote monitoring in heart failure patients. Our physicians are leaders in using device diagnostics and remote monitoring technology. Recent work from our investigators has resulted in the creation of a predictive algorithm for patient response and long-term outcome

Conditions & Diseases

The care team at the Corrigan Minehan Heart Center encourages all patients and family members to learn more about conditions and diseases that affect the heart and overall cardiovascular system. The links below provide more information about heart conditions and diseases that might be treated within this program.

  • Arrhythmias

    Arrhythmias are heart rhythm disorders that may originate in the atria (the receiving chambers of the heart) or the ventricles (the pumping chambers of the heart).

  • Cardiomyopathy

    Cardiomyopathy is any disease of the heart muscle in which the heart loses its ability to pump blood effectively.

  • Heart Failure

    Heart failure, also called congestive heart failure, is a condition in which the heart cannot pump enough oxygenated blood to meet the needs of the body's other organs.

Patient Education

Mass General is dedicated to ensuring that people understand their health care choices and have the necessary information to make decisions affecting their health and well being. The related support and wellness information listed below can play a role in treatment options.

  • Patient Guide to Cardiac Surgery (PDF)

    Learn what to expect before, during and after your surgery at the Massachusetts General Hospital Heart Center by downloading and printing our patient guide to cardiac surgery.

  • Understanding and Preparing for a Catheterization Procedure (PDF)

    As you prepare for your catheterization, Massachusetts General Hospital clinicians want you to feel as comfortable as possible. To help you understand what to expect during your visit, this booklet describes key steps of your catheterization procedure.

  • Frequently Asked Questions About Cardiac Anesthesia

    The Massachusetts General Hospital Heart Center offers a patient guide to cardiac anesthesia. Our dedicated clinicians believe it is important for you to know what to expect before, during and after a cardiac anesthesia.

  • Visitor's Guide to Cardiac Surgery

    Cardiac nurses at the Massachusetts General Hospital Heart Center offer support and guidance during a family member's open-heart surgery or transplantation.

  • Heart Failure Education Classes

    Clinicians at the Massachusetts General Hospital Corrigan Minehan Heart Center invite patients with heart failure and their families to attend a series of heart failure education classes.


  • In a Heartbeat - 7/16/2012, Mass General

    The team-based approach of the Institute for Heart, Vascular and Stroke Care ensures physicians approach complex situations from all angles, providing cohesive multidisciplinary care.

  • Improved Clinical Outcomes for CRT Patients - 6/6/2012, Mass General

    Jagmeet Singh, MD, Director of the Cardiac Resynchronization Therapy Program at the Massachusetts General Hospital Heart Center, discusses his team’s recent study about multidisciplinary care (MC) versus conventional care (CC) in CRT (cardiac resynchronization therapy) patients.

  • MGH goes red for women’s heart health - 2/18/2011, Mass General

    MGH Hotline 2.18.11 Just in time for Valentine’s Day, the MGH Heart Center and Corrigan Women’s Heart Health Program brought attention to hearts everywhere by celebrating “Go Red for Women” month with a series of events and activities to raise awareness of heart disease in women.

  • New heart monitoring device may prevent hospitalizations, empower patients with heart failure - 5/17/2010, Mass General

    It’s estimated that more than 5 million Americans are affected by heart failure—a condition characterized by the slow, progressive deterioration of the heart’s pumping ability. The syndrome occurs when the ventricles become too weak to pump sufficient blood to the body or when the ventricles become stiff, hindering blood from filling the heart. Often, heart failure is accompanied by a buildup of fluid pressure in the pulmonary blood vessels.

  • At home heart failure care - 7/21/2009, Mass General

    A new clinical trial at the Massachusetts General Hospital Heart Center gives patients the power to monitor their hearts and change their medication dosing daily to prevent the symptoms of heart failure.

  • Monitoring patients remotely - 7/16/2009, Mass General

    New wireless technology allows Heart Center clinicians to keep tabs on heart failure patients wherever they are.

  • A strongman's second chance - 6/4/2009, Clinical

    In 2008, the Massachusetts General Hospital Transplant Center completed the most heart transplants in the region. Personal trainer and strongman competitor, Jim Murphy, is one shining example of the great successes of the program.


  • An advanced cardiac CT scanner

    An advanced cardiac CT scanner

    Physicians at the Massachusetts General Hospital Heart Center use leading-edge technology to identify possible cardiac abnormalities.

  • Resynching a Heart — and a Life: Bob's Story

    Resynching a Heart -- and a Life: Bob's Story

    Jane and Bob Wass have been married for 59 years and rarely leave one another’s side. Jane left Bob at home for 35 minutes one afternoon and, when she returned, she found Bob had collapsed from a heart attack. They went to Mass General, where they learned he had a dyssynchrony. Bob's care team implanted a pacemaker and defibrillator, and he experienced an immediate improvement in his health. The team continues to monitor Bob’s heart remotely.


Contact Us

Corrigan Minehan Heart Center

55 Fruit Street Boston, MA 02114
  • Near Public Transit
  • Handicapped Accessible
  • Phone: 866-644-8910

If you are a new patient, you may call the Corrigan Minehan Heart Center outpatient access office at 866-MGH-8910, or complete our online appointment form to request an appointment. A member of our access team will ask you more about your condition and symptoms, and match you with the best-fitting Corrigan Minehan Heart Center physician.

Request an appointment Request a second opinion

Call to request an appointment or referral 866-644-8910

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