John Wen-Yueh (John) Chen, MD, PhD
- Clinical Interests
- Multiple sclerosis
- Neurodegenerative disorders
- Boston: Massachusetts General Hospital
- Medical Education
- MD, University of Illinois College of Medicine
- PhD, University of Illinois College of Medicine
- Residency, Massachusetts General Hospital
- Fellowship, Massachusetts General Hospital
- Board Certifications
- Diagnostic Radiology, American Board of Radiology
- Neuroradiology, American Board of Radiology
- Foreign Languages
- Accepting New Patients
- Insurances Accepted
- Aetna Health Inc.
Blue Cross Blue Shield - Indemnity
Blue Cross Blue Shield - Managed Care
Blue Cross Blue Shield - Partners Plus
Cigna (PAL #'s)
Fallon Community HealthCare
ForMost Managed Care
Great-West Healthcare (formally One Health Plan)
Harvard Pilgrim Health Plan - PBO
Health Care Value Management (HCVM)
Humana/Choice Care PPO
Neighborhood Health Plan - ACD
Neighborhood Health Plan - PBO
OSW - Connecticut
OSW - Maine
OSW - New Hampshire
OSW - Rhode Island
Private Health Care Systems (PHCS)
Tufts Health Plan
Tufts Medicare Advantage PPO
United Healthcare (non-HMO) - ACD
United Healthcare (non-HMO) - PBO
BiographyDr. Chen is an Assistant Professor at Harvard Medical School and Attending Clinician (Neuroradiology) at MGH. Dr. Chen is a graduate of the University of Illinois (MD, PhD in physical chemistry) and completed his radiology residency in 2004 and neuroradiology fellowship at MGH in 2005. He has won several awards including the MGH Wyman Award, RSNA and Dana Foundation Awards, as well as an NIH K08 award. His current research is supported by two NIH R01 and an R21 grants.
My laboratory studies neuroinflammation, combining basic science research with a clinical focus. In particular, we investigate the roles of molecular pathways and innate immune processes related to microglia in multiple sclerosis but also other diseases where CNS inflammation is prominent. A key aspect of our research is in deciphering complex in vivo biology by using innovative molecular imaging technologies, targeted molecular treatments, advanced experimental models as well as human trials. Ultimately we hope advance the diagnosis and treatment of these diseases by developing novel imaging and treatment strategies.
Tracking the Inflammatory Response in Stroke in Vivo by Sensing the Enzyme Myeloperoxidase
P Natl Acad Sci U S A. 2008;105 (47):18584-18589
Myeloperoxidase-targeted imaging of active inflammatory lesions in murine experimental autoimmune encephalomyelitis.
Brain. 2008;131(Pt 4):1123-33
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