Lipid Metabolism

The Lipid Metabolism Unit engages in both clinical and research activities centering on the role of lipids and lipoproteins in artherosclerosis (heart disease).


Lipid Metabolism Unit
Jackson Building
Room 1326
32 Fruit Street
Boston, MA 02114

Phone: 617-726-5906

About Us Clinical ActivitiesThe clinical effort centers on the MGH Lipid Associates, where patients with disorders affecting their blood cholesterol and triglyceride levels are diagnosed and treated. The Lipid Associates participate  in clinical trials of novel lipid-lowering agents, and performs studies on the genetics of lipid disorders.

ResearchThe research activities of the Lipid Metabolism Unit are centered on cholesterol trafficking in and out of cells and the proteins that control this movement. NIH funded studies support current investigations into the biology of the ABCA family of lipid transporters, scavenger receptors, and inflammatory signaling pathways that play a role in atherosclerosis and Alzheimer's disease. The Lipid Metabolism Unit is tightly linked into the Center for Computational & Integrative Biology (CCIB), which has developed a new program in Translational Medicine, headed by Mason Freeman MD, is designed to take novel therapeutic molecules generated in either the CCIB laboratories or elsewhere in academia or industry and move those treatments into first-in-man therapeutic trials.