Physician Photo

James Benjamin Meigs, MD

  • Phone: 617-724-2700
Primary Care
Department of Medicine
Clinical Interests
Internal Medicine
Primary Care Medicine
Boston: Massachusetts General Hospital
Medical Education
MD, Harvard Medical School
Residency, Massachusetts General Hospital
Fellowship, Massachusetts General Hospital
Board Certifications
Internal Medicine, American Board of Internal Medicine
Patient Age Group
Accepting New Patients
Not Accepting New Patients


James Meigs, MD, MPH, is Professor of Medicine at Harvard Medical School and Massachusetts General Hospital and Co-Director of the Mass General Clinical Research Program's Clinical Effectiveness Research Group.

He has mentored 50 junior clinical research investigators, supported in part by an NIDDK K24 award. In 2009, he was awarded the American Diabetes Association's Kelly West Award for Outstanding Achievement in Diabetes Epidemiology. He is past Associate editor for Diabetes Care and serves on many national scientific committees. Also, for more than 25 years, he has been a practicing primary care general internist in the Mass General Internal Medicine Associates.

ResearchDr. Meigs' research interest for more than 20 years has been the cause and prevention of type 2 diabetes and cardiovascular disease using molecular and genetic epidemiology and translational health services research approaches. He has authored more than 400 peer-reviewed scientific papers, supported by multiple National Institutes of Health and foundation research grants.


Selected publications:

  1. Berkowitz SA, Meigs JB, Wexler DJ. Age at type 2 diabetes onset and glycaemic control: results from the National Health and Nutrition Examination Survey (NHANES) 2005-2010. Diabetologia. 2013 Sep 1. [Epub ahead of print] PMID: 23995472
  2. DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet. 2014 Mar;46(3):234-44. PMID: 24509480
  3. Vassy JL, Hivert MF, Porneala B, Dauriz M, Florez JC, Dupuis J, Siscovick DS, Fornage M, Rasmussen-Torvik LJ, Bouchard C, Meigs JB. Polygenic type 2 diabetes prediction at the limit of common variant detection. Diabetes. 2014 Feb 11. [Epub ahead of print] PMID: 24520119
  4. Cornes BK, Brody JA, Nikpoor N, Morrison AC, Dang HCP, Ahn BS, Wang S, Dauriz M, Barzilay JI, Dupuis J, Florez JC, Coresh J, Gibbs RA, Kao WHL, Liu C-T, McKnight B, MuznyD, Pankow JS, Reid JG, White CC, Johnson AD, Wong TY, Psaty BM, Boerwinkle E, Rotter JI, Siscovick DS, Sladek R, Meigs JB. Association of Levels of Fasting Glucose and Insulin with Rare Variants at the Chromosome 11p11.2-MADD Locus: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study. Circulation Cardiovascular Genetics 2014, in press.
  5. Meigs JB, Grant RW, Piccolo R, Lopez L, Florez JC, Porneala B, Marceau L, McKinlay JB. Association of African Genetic Ancestry with Fasting Glucose and Hemoglobin A1c Levels in Non-Diabetic Individuals: The Boston Area Community Health (BACH) Prediabetes Study. Diabetologia 2014; in press.

Weight gain after quitting smoking does not negate health benefits

A recent MGH study analysis may have answered a question that has troubled individuals considering stopping smoking: do the health effects of any weight gained after quitting outweigh the known cardiovascular benefits of smoking cessation?

Weight gain after quitting smoking does not negate health benefits

An analysis of data from the Framingham Offspring Study confirms that the health benefits of quitting smoking far exceed any negative effects of weight gained after smoking cessation

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Phone: 617-724-2700