Physician Photo

Paul Borchyung Yu, MD, PhD

  • Phone: 617-724-6760
Department of Medicine


  • Heart Center
  • Non-invasive Cardiology
  • General Clinical Cardiology
  • Coronary Artery Disease Program
Clinical Interests
Pulmonary arterial hypertension
Vascular calcification
Boston: Massachusetts General Hospital
Medical Education
PhD, Duke University
MD, Duke University School of Medicine
Residency, University of California San Francisco
Fellowship, Massachusetts General Hospital
Board Certifications
Cardiovascular Disease, American Board of Internal Medicine
Foreign Languages
Patient Age Group
Accepting New Patients

BiographyDr. Paul Yu completed his A.B. in Philosophy and a B.S. in Biological Sciences at Stanford University. He subsequently completed M.D. and Ph.D. (Immunology) degrees at Duke University, followed by Internal Medicine residency training at the University of California at San Francisco, and clinical and research fellowships in Cardiovascular Disease at Massachusetts General Hospital. Dr. Yu joined the faculty in Cardiology and the Cardiovascular Research Center in 2006. Dr. Yu is board certified in Internal Medicine and Cardiovascular Medicine, and is Assistant Professor of Medicine at Harvard Medical School.


Dr. Yu maintains a clinical practice in general cardiology, seeing patients with known coronary artery disease or who have significant risk factors, patients with heart failure, and patients with heart rhythm disturbances. Dr. Yu has a special interest in pulmonary vascular disease. Heis particularly interested in how certain individuals are predisposed to developing vascular diseases such as pulmonary arterial hypertension or vascular calcification.

A major effort of Dr. Yu's laboratory is focused on understanding how certain signaling pathways, including the bone morphogenetic protein (BMP) and transforming growth factor beta (TGF-beta) pathways, may be dysregulated in pulmonary vascular disease, and vascular calcification. These signals are thought to determine how vascular progenitor cells grow and mature, and may contribute to conditions in which the vessel wall functions abnormally, or develops lesions which interfere with its normal function.

Cardiac Unit Associates
55 Fruit Street
Boston, MA 02114-2696

Phone: 617-724-6760
Fax: 617-724-6767