BiographyZamaneh Mikhak, MD, received a B.A. in Biology from Boston University in 1987 and an MD from University of Pennsylvania School of Medicine in 1991. She subsequently completed a pediatric internship and residency at Children's National Medical Center in Washington, DC, in 1994 and an allergy/immunology fellowship at Children's Hospital Boston in 1998. Dr. Mikhak has devoted much of her career to the care of pediatric patients with atopic disorders as well as basic and translational research. She is the author of numerous publications and the recipient of numerous awards and NIH grants.
ResearchBasic and translational research with a focus on T cells, dendritic cells and lung immunology.
Mikhak Z, Strassner JP, Luster AD. Lung dendritic cells imprint T cell lung homing and promote lung immunity through the chemokine receptor CCR4. Journal of Experimental Medicine. 2013 Sep;210(9):1855-1869.
Mikhak Z,Luster AD. The emergence ofbasophils as antigen-presenting cells in Th2 inflammatory responses. J Mol Cell Biol. 2009 Dec;1(2):69-71.
Mikhak Z, et al. Endotoxinaugmented antigen-induced Th1 cell trafficking amplifies airway neutrophilicinflammation. J Immunol. 2009 Jun15;182(12):7946-56.
Mikhak Z, et al. Contribution of CCR4 and CCR8 toantigen-specific T(H)2 cell trafficking in allergic pulmonary inflammation. J Allergy Clin Immunol. 2009Jan;123(1):67-73.e3. Epub 2008 Dec 4.
Mikhak, Z,Luster AD. Chemokines in cellmovement and inflammation. Middleton's Allergy (7th Ed).
Mikhak Z, et al. Immunoglobulin deficiency in Stickler syndrome. Am J Med Genet A. 2006 Dec15;140(24):2824-7.
Mikhak Z. Dose-response studies of fluticasonepropionate and budesonide: classification based on asthma severity. Allergy Asthma Proc. 2006Sep-Oct;27(5):402-11.
Mikhak Z, et al. STAT1 in peripheral tissuedifferentially regulates homing of antigen-specific Th1 and Th2 cells. J Immunol. 2006 Apr 15;176(8):4959-67.
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