Massachusetts General Hospital

Research

Dr. Makimura is interesting in investigating the neuroendocrine regulation of body weight and its associated co-morbidities. Dr. Makimura has previously performed investigations using mice models of obesity and more recently has initiated clinical investigations into the role of growth hormone in human obesity and cardiovascular disease. Dr. Makimura is also interested in the the use of non-invasive imaging techniques to study the role of mitochondria in mediating metabolic complications associated with obesity.

Publications

View my most recent publications at PubMed

Please view my complete publication record on PubMed.

Relationship between Monocyte/Macrophage Activation Marker Soluble CD163 and Insulin Resistance in Obese and Normal-Weight Subjects.

Zanni MV, Burdo TH, Makimura H, Williams KC, Grinspoon SK. Clin Endocrinol (Oxf). 2011 Nov 19. doi: 10.1111/j.1365-2265.2011.04284.x. [Epub ahead of print]

Reduced growth hormone secretion in obesity is associated with smaller LDL and HDL particle size.

Makimura H, Feldpausch MN, Stanley TL, Sun N, Grinspoon SK. Clin Endocrinol (Oxf). 2012 Feb;76(2):220-7. doi: 10.1111/j.1365-2265.2011.04195.x.

Obesity: Cure obesity: sleep more, eat out less and turn down the heat?

Makimura H. Nat Rev Endocrinol. 2011 Jun;7(6):318-9. Epub 2011 Mar 29. No abstract available.