Physician Photo

Hideo Makimura, MD, PhD

Assistant Professor of Medicine

  • Phone: 617-726-7948
Department of Medicine
Clinical Interests
Pituitary tumors
Hypothalamic obesity
Boston: Massachusetts General Hospital
Medical Education
MD, PhD, Mount Sinai School of Medicine
Residency, Beth Israel Deaconess Medical Center
Fellowship, Massachusetts General Hospital
Board Certifications
Internal Medicine, American Board of Internal Medicine
Endocrinology, Diabetes & Metabolism, American Board of Internal Medicine
Foreign Languages
Patient Age Group
Accepting New Patients

BiographyHideo Makimura, MD, PhD is a clinician in the Neuroendocrine Clinical Center and faculty member in the Neuroendocrine Unit at the Massachusetts General Hospital, and an Assistant Professor of Medicine at Harvard Medical School.  He is a clinical researcher who sutides obesity with a focus on metabolism and growth hormone.  He is an author of more than 35 peer-reviewed publications and has won several awards including the Early Investigators Award from the Endocrine Society.


Dr. Hideo Makimura is a clinical/translational researcher who studies obesity and its cardio-metabolic complications, with a focus on growth hormone and mitochondria.  He performs detailed human physiology studies utilizing deep phenotyping techniques to address complex metabolic questions.  His current research focuses on nutritional, hormonal and metabolic regulation of skeletal muscle mitochondria and its role in cardio-metabolic disease in obesity.


View my most recent publications at PubMed

Please view my complete publication record on PubMed.

Metabolic effects of a growth hormone-releasing factor in obese subjects with reduced growth hormone secretin: a randomized controlled trial. Makimura H, Feldpausch MN, Rope AM, Hemphill LC, Torriani M, Lee H, Grinspoon SK. J clin Endocrinol Metab. 2012; 97 (12): 4769-79

Reduced growth hormone secretion is associated with increased carotid intima-media thickness in obesity. Makimura H, Stanley T, Mun D, Chen C, Wei J, Connelly JM, Hemphill LC, Grinspoon SK. J Clin Endocrinol Metab. 2009; 94 (12): 5131-8.

The effects of central adiposity on growth hormone (GH) response to GH-releasing hormone-arginine stimulation testing in men. Makimura H, Stanley T, Mun D, You SM, Grinspoon S. J Clin Endocrinol Metab. 2008; 93 (11): 4254-60.

Central diabetes insipidus: a previous unreported side effect of temozolomide. Faje AT, Nachtigall L, Wexler D, Miller KK, Klibanski A, Makimura H. J Clin Endocrinol Metab. 2013; 98 (10): 3926-31.

Obesity: Cure obesity: sleep more, eat out less and turn down the heat? Makimura H. Nat Rev Endocrinol. 2011; 7 (6): 318-9.

Neuroendocrine Clinical Center
Zero Emerson Place
Suite 112
Boston, MA 02114-2217

Phone: 617-726-7948
Fax: 617-726-1241

Medical Walk In Unit
15 Parkman Street
Boston, MA 02114-3117

Phone: 617-726-2707
Fax: 617-724-0189