My research is focused on the epidemiology and outcomes of patients with inflammatory bowel diseases. I am involved in studies that are aimed to better understand the risk factors (including diet and environment) for developing Crohn's disease or ulcerative colitis. This will help us better understand the pathogenesis of these conditions which will eventually lead to novel treatments. I am also conducting clinical research that examines the course of disease and response to various therapies with the aim of developing predictive models that can be used both to inform about disease course as well the likelihood of response to specific therapy. I am interested in novel tools to monitor disease activity and identify complications. I participate in clinical trials related to inflammatory bowel diseases. I am also involved in various research projects using large datasets to determine patterns of care and outcome as they relate to gastroenterology.
Research at the Massachusetts General Hospital Digestive Healthcare Center, including clinical trials of new biologic medications, as well new minimally invasive surgical techniques, is helping expand treatment and management of patients with inflammatory bowel disease.