Since 1994, the
The CEPAC team collaborates with research teams in Botswana, Brazil, Côte d’Ivoire, France, India, Mozambique, South Africa, and Zimbabwe, as well as investigators from Brigham and Women’s Hospital, the Harvard School of Public Health, Weill Cornell Medical College, and Yale University. Research from the CEPAC team has been published in several leading medical journals, including the Journal of the American Medical Association, New England Journal of Medicine, and AIDS. For more information, visit .
For a full list of group members with research interests including fellows, software engineers, biostatisticians, project specialists, project coordinators, and research assistants, please visit.
At the center of CEPAC research is the CEPAC model. The CEPAC model simulates a large cohort of patients and follows each patient on a monthly basis until death. CEPAC uses published data on the natural history of HIV and opportunistic infections, as well as the efficacy and cost of prophylaxis and treatment along with other epidemiological parameters to simulate the overall impact of HIV on a specific population.
CEPAC researchers simulate prospective treatment strategies onto the cohort under varying epidemiological conditions and use the outputs to project a strategy’s efficacy and cost-effectiveness.
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