Neuroendocrine Clinical Center

The Neuroendocrine Clinical Center provides outpatient care with a multidisciplinary approach to patients with pituitary and hypothalamic disorders.

The Center is a national referral center for the evaluation and treatment of pituitary tumors, recurrent pituitary adenomas, and tumors or disorders of the hypothalamic-pituitary region. The Center is ideally suited for the referral of patients with pituitary tumors, including prolactinomas, Cushing's disease, acromegaly, nonfunctioning pituitary tumors, recurrent pituitary adenomas, and pituitary and hypothalamic disorders which lead to adrenal, thyroid, ovarian, or testicular deficiency. Patients can be referred for the development of a treatment plan in conjunction with their primary physician, for a second opinion, or for ongoing management by the Center physicians.

The Neuroendocrine Clinical Center offers detailed outpatient evaluation through comprehensive office visits, complete basal and dynamic hormone testing, and coordination of radiological studies and visual field evaluations. All new patients are presented at the weekly Neuroendocrine Clinical Conference which is attended by endocrinologists, neurosurgeons, neurologists, and radiation therapy physicians. A diagnostic and therapeutic plan is formulated for each patient and provided to the referring physician.

The Center have a team of Endocrinologists who are experienced in the chronic administration of replacement hormones and in the use of drugs which block hormone excess syndromes. They are experienced in the use of investigational drugs for the treatment of prolactin and growth hormone disorders. They have been at the forefront of medical therapy for pituitary disorders with the use of new dopamine agonists for prolactinomas and somatostatin analogues for acromegaly.  The Neurosurgical involvement in the Center ensures prompt surgical intervention when necessary and likewise input from the Department of Radiation Medicine facilitates the planning of therapy. Neurologists are available for the pharmacological treatment of headaches, seizures, and hypothalamic syndromes.   The Center also has a nurse who offers patient education, including teaching self-administration of medications requiring injection.

The physicians in the Neuroendocrine Clinical Center also work closely with the department of Neurosurgery to provide cohesive care for several innovative treamtments.  Many of our patients receive proton beam therapy and conventional radiation therapy for treatment of pituitary lesions. Laser-guided MR imaged stereotactic intrasellar tumor localization can be used for selected patients with untreated pituitary tumors, incomplete surgical resection, or tumor recurrence.  In addition, an intraoperative MRI has recently been installed in the MGH neurosurgical operating suite.  Unlike standard MRI facilities, this is a portable machine which is designed to be used in an operating room and provide real-time visualisation during all stages of brain surgery.   For more information, please visit the Department of Neurosurgery's website http://neurosurgery.mgh.harvard.edu/.

Areas in which the Neuroendocrine Clinical Center team of phsyicians provide special multidisciplinary expertise include:

    • Pituitary Tumors
      • Prolactinomas; Cushing's disease; Acromegaly; Non-functioning tumors; Recurrent pituitary adenomas.
    • Prolactin Disorders
      • Amenorrhea-Galactorrhea Syndrome; Drug-induced hyperprolactinemia; Infertility; Male hypogonadism.
    • Cushing's Disease
      • Pituitary Cushing's; Ectopic Cushing's; Adrenal Cushing's; Iatrogenic Cushing's, Recurrent Cushing's.
    • Hypopituitarism
      • Hypoadrenalism; Hypothyroidism; Hypogonadism; Growth hormone deficiency.
    • Posterior Pituitary Dysfunction
      • Diabetes insipidus; Syndrome of inappropriate antidiuretic hormone secretion.
    • Hormone Dependent Neurologic Disorders
      • Seizures; Headaches.
    • Hypothalamic Syndromes
      • Suprasellar Tumors; Craniopharyngiomas

Scheduling and Referrals: The Massachusetts General Hospital Neuroendocrine Clinical Center is located on the lst floor (Suite 112) of Zero Emerson Place, Boston, Massachusetts, (off Blossom Street) and directly across from the Massachusetts General Hospital Gray Lobby. (Select here for maps of MGH). Outpatient clinical visits and inpatient consultations can be arranged by calling the Neuroendocrine Clinical Center Office at (617) 726-7948. Physicians with questions may contact Dr. Nachtigall at (617) 726-7948.

    Special Instructions (If available, please bring):

    • Copies of your medical records/discharge summary/physician notes
    • a copy of your X rays
    • a copy of your lab reports
    • If you are presently under medications, bring them with you to your appointment
    • Reminder: Please bring your current blue hospital card to your appointment. If you do not have a card or your card needs to be updated, please go to one of the registration areas at least 20 minutes prior to your appointment. Thank you.

Speakers

    The Neuroendocrine Clinical Center offers speakers on a wide variety of topics. Lectures, rounds, and small symposia can be arranged.

Neuroendocrine Clinical Conference

    A weekly interdisciplinary conference is held to discuss all new patients referred to the Neuroendocrine Clinical Center and to review patient management issues. It is a multidisciplinary conference, attended by the members of the Neuroendocrine, Neurology, Neurosurgery, and Radiation Medicine services. Physicians are welcome to attend and present cases.

Neuroendocrine Lecture Series

    A bimonthly conference is held on didactic and research topics related to Neuroendocrinology. Attendance at this series is open to all interested medical personnel.

MGH Russell Museum Lunchtime Lecture Series

Paul S. Russell, MD Museum of Medical History and Innovation invites you to attend its latest lecture in its lunchtime series

Speakers

    The Neuroendocrine Clinical Center offers speakers on a wide variety of topics. Lectures, rounds, and small symposia can be arranged.

Neuroendocrine Clinical Conference

    A weekly interdisciplinary conference is held to discuss all new patients referred to the Neuroendocrine Clinical Center and to review patient management issues. It is a multidisciplinary conference, attended by the members of the Neuroendocrine, Neurology, Neurosurgery, and Radiation Medicine services. Physicians are welcome to attend and present cases.

Neuroendocrine Lecture Series

    A bimonthly conference is held on didactic and research topics related to Neuroendocrinology. Attendance at this series is open to all interested medical personnel.

Neuroendocrine Unit

Zero Emerson Place
Suite 112
Boston, MA 02114

Phone: 617-726-7948