• Michal Arbel, MSc, PhD

    Michal Arbel, MSc, PhD Dr. Arbel is a former Alzheimer’s Disease Research Unit fellow in the Neurology Department’s MassGeneral Institute for Neurodegenerative Disease, where she continues her research. She is a member of the Hyman Lab.
  • Bacskai, Brian, PhD, Professor of Neurology

    Brian Bacskai, PhD Dr. Bacskai's research is aimed at optimizing anti-amyloid-beta therapeutic approaches and--using multiphoton microscopy--imaging the anatomy and physiology of specific cell types in the brain before and after treatment.
  • Berezovska, Oksana, PhD, Associate Professor of Neurology

    Oksana Berezovska Dr. Berezovska's research goal is to study the cellular and molecular mechanisms of Alzheimer's disease pathology. Her lab analyzes gamma-secretase and APP interactions, examining mechanisms by which certain factors modulate A beta production and/or regulate the precision of APP cleavage by gamma-secretase.
  • Paolo Ciccarese, Instructor in Neurology

    Paolo Ciccarese Paolo Ciccarese, PhD, is a member of the MIND Center for Interdisciplinary Informatics research core lab. His goal is to limit the episodes of lost knowledge in biomedical research and help scientists to capitalize on what is already known. His current work is on scientific discourse representation models, and annotation of digital resources in Alzheimer's disease research.
  • Cudkowicz, Merit, MD, MSc, Professor of Neurology

    Merit Cudkowicz Dr. Cudkowicz's research and clinical activities are dedicated to the study and treatment of patients with neurodegenerative disorders, in particular amyotrophic lateral sclerosis (ALS) and Huntington’s Disease (HD).
  • Gomez-Isla, Teresa, PhD, Associate Professor of Neurology

    Teresa Gomez-Isla Dr. Gomez-Isla’s research includes basic science using transgenic mouse models of Alzheimer’s disease and dementia, analyzing data on clinical, neuroimaging and genetic features of demented patients and healthy controls. She also manages multiple clinical trials.
  • Guenette, Suzanne, PhD, Assistant Professor of Neurology

    Suzanne Guenette Dr. Guénette’s research focuses on the molecular pathways that impact amyloid precursor protein (APP) function, as well as the generation and degradation of b-amyloid, a peptide central to the etiology of Alzheimer’s disease.
  • Kazantsev, Alex, PhD Associate Professor of Neurology

    Alex Kazantsev Dr. Kazantsev's laboratory is focused on discovery therapeutic agents for Huntington's and Parkinson's diseases using methods of high throughput screening, rational drug design, and medicinal chemistry lead optimization.
  • Kim, Doo Yeon, PhD, Assistant Professor of Neurology

    Doo Yeon Kim Dr. Doo Yeon Kim, of the Genetics and Aging Research Unit, is part of Dr. Dora Kovac's team, studying beta-secretase (BACE), an enzyme in the brain which can release small fragments of the amyloid precursor protein (APP), the main ingredient for Alzheimer’s plaques.
  • Vanderburg, Charles R., PhD, Instructor in Neurology

    Charles Vanderberg Dr. Vanderburg's current research focus is on the microgenomic and microproteomic profiling of human neuropathological tissue specimens and their derivatives, including miRNAs and exosomes.
  • Antonio Valencia, PhD

    Antonio Valencia, PhD Dr. Antonio Valencia is currently investigating Huntington’s disease (HD), focusing on cell survival pathways, oxidative damage, altered membrane function and neurodegeneration.
  • Brian J. Wainger, MD, PhD

    Brian J. Wainger, MD, PhD The aim of the Wainger Laboratory is to ask clinically relevant research questions that could lead to rapid translation and innovation for treating diseases of the motor and sensory nervous systems.
  • Young, Anne B., MD, PhD, Professor of Neurology, Director, MIND

    Anne Young Dr. Young directs a comprehensive drug discovery program at MIND, which has been successful in identifying drug targets for Parkinson’s, Huntington’s and other neurodegenerative diseases. Her laboratory also studies the role of the protein alpha-synuclein,