There are aproximately 25 laboratories at the MassGeneral Institute for Neurodegenerative Disease. Led by physician-scientists, certain labs collaborate and share resources on key projects to speed up the pace of discovering new treatments, and one day, we trust, find cures.
Albers Lab at MIND - Mark W. Albers
The Albers’s Laboratory uses the olfactory system of mice and humans to elucidate early pathologic events of neurodegeneration.
Bacskai Lab at MIND
Brian Bacskai's laboratory uses sophisticated optical techniques to address fundamental questions in Alzheimer's disease research.
Berezovska Lab - Presenilin Group Alzheimer Research Unit
The research goal of Dr. Berezovska's lab is to study the cellular and molecular mechanisms of Alzheimer's disease pathology.
Clark Lab
MIND Informatics develops and applies integrative computational methods in biomedical and brain research, working with leading clinicians and researchers to understand and cure neurological disorders.
Difiglia Laboratory - Cellular Neurobiology
Marian M. DiFiglia, PhD, is investigating the role of the HD mutation in the molecular and cellular events leading to neurodegeneration.
Frosch Lab
My laboratory is interested in the development and characterization of animal models of human neurodegenerative diseases, particularly Cerebral amyloid angiopathy (CAA), Alzheimer and Parkinson diseases.
Gomez-Isla Lab
Dr. Gomez-Isla investigates the neurobiology of normal aging, Alzheimers, and other dementias.
Hersch Laboratory, Steven M. Hersh, MD, PhD
Led by Dr. Hersch, the Laboratory investigates Huntington’s disease using transgenic mouse models and human brain tissue. Research also includes HD clinical trials.
Hyman Lab
The Hyman lab focuses on research in neural system failure underlying cognitive loss in Alzheimer’s disease.
Kazantsev Drug Discovery Lab
The Kazantsev lab is focused on discovering therapeutic agents for Huntington's and Parkinson's diseases using high throughput screening, rational drug design, and medicinal chemistry lead optimization.
Kovacs Lab, Neurobiology of Disease Laboratory at MIND
Molecular research of neurodegeneration in Alzheimer’s disease (AD) focused on identifying cellular pathways regulating the generation of the toxic beta-amyloid protein (Abeta).
Krainc Lab
The Krainc laboratory utilizes molecular and genetic approaches to identify key molecular targets for the development of neuroprotective therapies for Huntington’s, Parkinson’s and related neurodegenerative diseases.
Moir Lab
Dr. Robert Moir's research focuses on the biochemical and cellular mechanisms involved in neurodegeneration in Alzheimer's disease and aging.
Sadri-Vakili Neuroepigenetics Laboratory
The laboratory focuses on identifying epigenetic alterations that regulate gene expression in brain disorders, and investigates whether these alterations are heritable across multiple generations.
Schwarzschild Lab - Molecular Neurobiology Laboratory
The Schwarzschild lab targets three purines—adenosine, caffeine and urate—in pursuit of improved therapy for Parkinson’s and related neurodegenerative diseases.
Tannous Lab - Experimental Therapeutics and Molecular Imaging Laboratory
Bakhos Tannous, PhD – Research focus in molecular Imaging, gene transfer technologies and high throughput screening aiming at finding novel therapeutics against brain tumors.
Tanzi Lab - Genetics and Aging Research Unit
Dr. Rudolph Tanzi is carrying out genome-wide association screens to identify novel genes associated with AD and autism spectrum disorders.
Young Laboratory - Anne B. Young, MD
Dr. Young’s laboratory is examining the role of the protein alpha-synuclein, which plays a key role in the death of dopamine-producing brain cells in the Parkinson’s disease and other diseases with similar symptoms.
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