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Neurology Access Center 1-855-MGH-NEUR (644-6387)
The Neurological Clinical Research Institute (NCRI) was co-founded in 1994 by Dr. Merit Cudkowicz and Dr. Steven Greenberg to conduct clinical research in neurological disorders. The NCRI develops, designs, supports and manages innovative observational and interventional trials for neurological disorders. In collaboration with the Study Monitoring and Outcome Measures Center at SUNY Upstate Medical Center and the Mass General Biostatistics Center, the NCRI has an impressive record of rapidly and efficiently organizing, overseeing, coordinating, and conducting small and large multi-center, international clinical trials including randomized, double-blind, double-dummy and open label designs.The mission of the NCRI is to accelerate translational research in neurological disorders through initiating and testing novel therapies. The NCRI fulfills this mission by supporting the entire therapeutic development process, including:· Mapping the clinical development of potential therapies;· Custom design of clinical research protocols;· Bringing efficiency strategies and infrastructure to clinical research;· Providing resources, experienced staff, and services to accelerate the conduct of clinical research;· Fostering and empowering scientific collaboration;· Creating partnerships among scientific leaders with complementary backgrounds;· Establishing and managing disease-specific research consortia;· Performing high quality site-level clinical research;· Educating and mentoring future leaders in the field of clinical research; and· Encouraging scientific innovation through funding.Northeast ALS Consortium (NEALS)The NCRI serves as a Coordinating Center for the Northeast ALS Consortium (NEALS), a non-profit, research consortium committed to the cooperative implementation, timely completion, analysis, and reporting of clinical trials and other research studies aimed at improving patient care and understanding of the disease process of Amyotrophic Lateral Sclerosis (ALS). Together, the two entities have supported/conducted 19 clinical research studies in ALS.Dr. Merit Cudkowicz co-founded and co-directs the NEALS Consortium. The NEALS Consortium was formed with the goal of bringing together leading ALS scientists and clinicians caring for ALS patients, to offer advice on the selection of the best therapies and direction of ALS research. Today there are 103 medical sites and more than 400 members across North America.Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT)
The NCRI serves as the Clinical Coordinating Center for the Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT), an National Institute of Neurological Disorders and Stroke (NINDS) initiative which provides a robust, standardized, and accessible infrastructure to facilitate rapid development and implementation of protocols in neurological disorders affecting adult and/or pediatric populations. Today there are 25 sites nationally.
The NCRI's four cores consist of:
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