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My research focuses on the transcriptional regulation of blood cell development.
My research focuses on the transcriptional regulation of blood cell development. We especially are interested in the identification of key transcription factors in hematopoietic stem cell (HSC) and progenitor cell development. Particular emphasis is on the role of ZBP-89, SCL, Dusp22 as well as integrins in HSC development. We are currently utilizing multidisciplinary approaches to understand how these transcription factors regulate HSC fate determination. These methods include zebrafish, murine embryonic stem cell and mouse models as well as biochemical assays.
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