Dr. Arnaout is a physician-scientist in the Department of Medicine at Massachusetts General Hospital in Boston. He is Chief-Emeritus of the Division of Nephrology at Massachusetts General Hospital, and Professor of Medicine at Harvard Medical School.
BiographyDr. Arnaout received his medical degree with distinction from the American University of Beirut, Lebanon. He served on the medical staff of the American University of Beirut Hospital as an intern and resident in Medicine before moving to Johns Hopkins where he completed his residency. He then moved to Harvard where he finished fellowships in immunology and nephrology at Boston's Childrens Hospital and Brigham and Women's Hospital. Dr. Arnaout is a physician-scientist and served as Chief of the Division of Nephrology at Massachusetts General Hospital from 1998-2013. He currently serves as Director of Leukocyte Biology & Inflammation Program and the Structural Biology Program in the Department of Medicine and Nephrology at Massachusetts General Hospital.
Our laboratoryis interested in elucidating the molecular basis of human disease and in usingthis information to guide development of new and safer therapies. We utilizestate of the art technologies, including genetics, genomics, biochemistry, cellbiology, structural and computational biology and animal models of disease. Areas of interest include integrinbiology and structure, pathogenesis of autosomal dominant polycystic kidneydisease, lineage commitment in hematopoietic stem cells, mechanisms of ischemic kidney injuryand regeneration and engineering kidney assistdevices.
MGH investigators may have found a way to solve a problem that has plagued a group of drugs called ligand-mimicking integrin inhibitors, which have the potential to treat conditions ranging from heart attacks to cancer metastasis.
Phone 2: 617-726-5663