Mass General Hospital Nephrology Department

Resistant Hypertension Program

The Resistant Hypertension Program at Massachusetts General Hospital specializes in the evaluation, diagnosis and management of patients with resistant or difficult to treat hypertension.
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To request an appointment call: 866-644-8910


The divisions of Nephrology, Cardiology and Endocrinology, and the Corrigan Minehan Heart Center and the Vascular Center, jointly offer a Resistant Hypertension Program which specializes in the evaluation, diagnosis and management of patients with resistant or difficult to treat hypertension. The American Heart Association defines Resistant Hypertension as blood pressure that remains above goal despite the use of three antihypertensive agents in full dose, one of which is a diuretic. Patients with Resistant Hypertension are at high risk for cardiovascular and other complications. The Mass General Resistant Hypertension Program provides a multidisciplinary approach to care, including pharmacologic and non-pharmacologic approaches to blood pressure control as well as interventional options. Services offered include:

  • Treatment of Resistant Hypertension
  • 24-hour Ambulatory Blood Pressure Monitoring
  • Diagnosis and Management of Secondary Hypertension
  • Evaluation of Difficult to Treat Hypertension in the context of Cardiovascular Disease
  • Evaluation and Management of Secondary Hypertension related to Endocrine Diseases
  • Diagnosis and Management of Renal Vascular Hypertension
  • Seamless care with referring physicians

Clinical Faculty

Nephrology and Interventional Nephrology

Cardiology and Inteventional Cardiology

Vascular Medicine

Nursing Staff

  • Maria Luongo, RN
  • Chris Pacheco, NP

Conditions & Diseases

The links below provide more information about the conditions and diseases that might be treated within this program.

  • Analgesic Nephropathy

    Analgesic nephropathy is a chronic kidney disease that gradually leads to end-stage renal disease and the need for permanent dialysis or a kidney transplant.

  • Diabetic Nephropathy (Kidney Disease)

    Nephropathy is the deterioration of the kidneys. The final stage of nephropathy is called end-stage renal disease, or ESRD.

  • End Stage Renal Disease (ESRD)

    Renal failure refers to temporary or permanent damage to the kidneys that results in loss of normal kidney function.

  • Glomerulonephritis

    Glomerulonephritis is a type of glomerular kidney disease in which the kidneys' filters become inflamed and scarred, and slowly lose their ability to remove wastes and excess fluid from the blood to make urine.

  • Glomerulosclerosis

    Glomerulosclerosis is the term used to describe scarring that occurs within the kidneys in the small balls of tiny blood vessels called the glomeruli.

  • Goodpasture Syndrome

    Goodpasture syndrome is a rare, autoimmune disease that can affect the lungs and kidneys.

  • Hematuria (Blood in the Urine)

    Hematuria is the presence of red blood cells (RBCs) in the urine.

  • Hemolytic Uremic Syndrome

    Hemolytic uremic syndrome is a rare condition that mostly affects children under the age of 10. It is often characterized by damage to the lining of blood vessel walls, destruction of red blood cells, and kidney failure.

  • Immunoglobulin A (IgA) Nephropathy

    IgA nephropathy is a chronic kidney disease that may progress over a period of 10 to 20 years, and can lead to end-stage renal disease.

  • Nephrotic Syndrome

    Nephrotic syndrome is a condition often characterized by the following: very high levels of protein in the urine, low levels of protein in the blood, swelling, especially around the eyes, feet, and hands, as well as high cholesterol.

  • Polycystic Kidney Disease

    Polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts filled with fluid in the kidneys.

  • Renal Vascular Disease

    Renal vascular disease is the name given to a variety of complications that affect the arteries and veins of the kidneys.

Clinical Trials



Contact Us

Renal Associates

Suite 302165 Cambridge Street Boston, MA 02114
  • Near Public Transit
  • Handicapped Accessible
  • Phone: 617-726-5050
  • Fax: 617-724-1122


  • Monday - Friday, 9:00 am-5:00 pm

Our Location

Request an appointment

To request an appointment call: 866-644-8910

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