Photo of Steven Kyle Grinspoon, MD

Steven Kyle Grinspoon, MD

  • Director, MGH Program in Nutritional Metabolism
  • Co-Director, Nutrition Obesity Research Center, Harvard


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Clinical Interests
  • Pituitary disease
  • Endocrine manifestations of AIDS
Medical Education
  • MD, University of Rochester School of Medicine and Dentistry
  • Residency, New York Presbyterian Hospital
  • Fellowship, Massachusetts General Hospital
Board Certifications
  • Endocrinology
  • Diabetes & Metabolism
  • Boston: Massachusetts General Hospital
Insurances Accepted
  • Aetna Health Inc.
  • Beech Street
  • Blue Cross Blue Shield - Blue Care 65
  • Blue Cross Blue Shield - Indemnity
  • Blue Cross Blue Shield - Managed Care
  • Blue Cross Blue Shield - Partners Plus
  • Centene/Celticare
  • Cigna (PAL #'s)
  • Fallon Community HealthCare
  • Great-West Healthcare (formally One Health Plan)
  • Harvard Pilgrim Health Plan - ACD
  • Harvard Pilgrim Health Plan - PBO
  • Harvard Pilgrim Health Plan - SSN
  • Health Care Value Management (HCVM)
  • Humana/Choice Care PPO
  • MassHealth
  • Medicare
  • Medicare - ACD
  • Neighborhood Health Plan - ACD
  • Neighborhood Health Plan - PBO
  • OSW - Maine
  • OSW - New Hampshire
  • OSW - Rhode Island
  • Private Health Care Systems (PHCS)
  • Senior Whole Health
  • TriCare
  • Tufts Health Plan
  • Unicare
  • United Healthcare (non-HMO) - ACD
  • United Healthcare (non-HMO) - PBO
Patient Age Group

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Steven K. Grinspoon, MD is a clinician in the Neuroendocrine Clinical Center and a faculty member in the Neuroendocrine Unit at the Massachusetts General Hospital, and a Professor of Medicine at Harvard Medical School.  He is a clinical researcher who studies hypothalamic control of body weight and fat distribution in obesity and lipodystrophy with a focus on the metabolic and cardiovascular consequences of visceral fat accumulation.  Awards in recognition of his work have included selection to the American Society for Clinical Investigation, the Association of American Physicians and the 2014 Daniel Ahrens Award for Translational Science Research by the Association of Clinical and Translational Science.  He is the author of more than 190 peer-reviewed publications and serves as the Co-Director of the Nutrition Obesity Research Center at Harvard and as the Director of the MGH Program in Nutritional Metabolism.

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Research & Publications

Research Summary
Dr. Grinspoon is a clinical researcher who studies the development of novel neuroendocrine strategies to reduce cardiovascular and metabolic risk associated with excess visceral fat, with a focus on the use of growth hormone releasing hormone (GHRH) to increase endogenous pulsatile GH, and selectively reduce visceral fat. His research interests include metabolic consequences of visceral fat accumulation in lipodystrophy and obesity.
Hadigan C, Yawetz S, Thomas A, Havers F, Sax PE, Grinspoon S.  Effects of Rosiglitazone on Metabolic Indices and Fat in HIV Lipodystrophy: A Randomized Controlled Trial.  Ann Intern Med. 2004; 140: 786 - 794.

Falutz J, Allas S, Blot K, Potvin D, Kotler D, Somero M, Berger B, Brown S, Richmond G, Fessel J, Turner R, Grinspoon S. Metabolic Effects of a Growth Hormone-Releasing Factor in HIV Patients. N Engl J Med 2007; 357:2359-70.

Lo J, You SM, Canavan B, Liebau J, Beltrani G, Koutkia P, Hemphill L, Lee H, Grinspoon S. Low Dose Physiologic Growth Hormone in HIV Patients with Abdominal Fat Accumulation: A Randomized Controlled Trial. JAMA. 2008; 300:509-519. PMCID: PMC2532757

Subramanian S*, Tawakol A*, Burdo T, Abbara S, Wei, J, Vijayakumar J, Corsini E, Abdelbarky A, Zanni M, Hoffman U, Williams K, Lo J?, Grinspoon S?. Arterial Inflammation in HIV-Infected Patients. JAMA 2012. Jul 25;308(4):379-86. PMCID: PMC3724172

Stanley TL, Feldpausch M, Oh J, Branch K, Lee H, Torriani M, Grinspoon SK. Effects of Tesamorelin on Visceral Fat and Liver Fat in HIV-infected Patients with Abdominal Fat Accumulation: A Randomized Clinical Trial. JAMA. 2014 Jul 23-30;312(4):380-9. PMID:25038357

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News & Events


Program in Nutritional Metabolism
55 Fruit Street
Boston MA, 02114-2696
Phone: 617-724-9109
Fax: 617-724-8998
Neuroendocrine Clinical Center
Zero Emerson Place
Suite 112
Boston MA, 02114-2217
Phone: 617-726-7948617-726-6813
Fax: 617-726-1241

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