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The Massachusetts General Hospital Neuroendocrine & Pituitary Clinical Center provides a multidisciplinary approach to patients with pituitary and hypothalamic disorders. Comprised of endocrinologists, neurologists, and neurosurgeons, the Neuroendocrine & Pituitary Clinical Center is a national referral center for the evaluation and treatment of pituitary tumors, recurrent pituitary adenomas, and tumors or disorders of the hypothalamic-pituitary region.
The center is ideally suited for the referral of patients with pituitary tumors, including prolactinomas, Cushing's disease, acromegaly, nonfunctioning pituitary tumors, recurrent pituitary adenomas and pituitary and hypothalamic disorders which lead to adrenal, thyroid, ovarian or testicular deficiency. Patients can be referred for the development of a treatment plan in conjunction with their primary physician, for a second opinion, or for ongoing management by the center physicians.
The Neuroendocrine Clinical Center offers detailed outpatient evaluation of all disorders affecting the endocrine function of the hypothalamus and pituitary gland, achieved through comprehensive office visits, complete basal and dynamic hormone testing, and coordination of radiological studies and visual field evaluations. Patients are presented at the weekly Neuroendocrine Clinical Conference which is attended by endocrinologists, neurosurgeons, neurologists, and radiation therapy physicians. A diagnostic and therapeutic plan is formulated for each patient and provided to the referring physician.
Areas in which the Neuroendocrine Clinical Center provides special multidisciplinary expertise include:
The Neuroendocrine Clinical Center offers Stereotactic Proton Radiosurgery, an innovative program utilizing proton beam therapy and conventional radiation therapy, for treatment of pituitary lesions. Our laser-guided MR imaged stereotactic intrasellar tumor localization can be used for selected patients with untreated pituitary tumors, incomplete surgical resection, or tumor recurrence.
Physicians with questions may contact Beverly Biller, MD or Anne Klibanski, MD at 617-726-3965 or 888-429-6863 or via email.
The Massachusetts General Hospital Neuroendocrine and Pituitary Clinical Center is a national referral center for patients with neuroendocrine disorders and conditions including evaluation and treatment of pituitary tumors, recurrent pituitary adenomas, and tumors or disorders of the hypothalamic-pituitary region.
We are situated within a large general hospital with a closely affiliated pediatric endocrinology program, as well as world renowned medical, surgical and subspecialty divisions. Our patients are followed through the course of treatment in a longitudinal fashion for ongoing management of their condition. Additionally, patients can be referred for the development of a treatment plan in conjunction with their primary physician or for a second endocrine opinion.
The Neuroendocrine and Pituitary Clinical Center is a national referral center ideally suited for patients with pituitary tumors including:
Endocrinologists in the center are experienced in the chronic administration of replacement hormones and in the use of drugs which block hormone excess syndromes. They are experienced in the use of investigational drugs for the treatment of prolactin and growth hormone disorders. They have been at the forefront of medical therapy for pituitary disorders with the use of new dopamine agonists for prolactinomas and somatostatin analogues for acromegaly.
Neuroendocrine and Pituitary Clinical Center neurologists are available for the pharmacological treatment of headaches, seizures, and hypothalamic syndromes; and our clinical nurse offers patient education, including teaching self-administration of medications requiring injection for all patients.
Schedule an appointment at the Neuroendocrine and Pituitary Clinical Center by calling 617-726-7948.
Acromegaly is a disorder of the pituitary gland which produces excess growth hormones and thus results in excessive growth, first in the hands and feet, as soft tissue begins to swell.
Amenorrhea is a menstrual condition characterized by absent menstrual periods for more than three monthly menstrual cycles.
Diabetes insipidus is a condition that results from insufficient production of the antidiuretic hormone (ADH), a hormone that helps the kidneys and body conserve the correct amount of water.
Empty sella syndrome is a condition where the bony structure that houses the pituitary gland is enlarged, sometimes resulting in high fluid pressure inside the skull.
Hypopituitarism, also called an underactive pituitary gland, is a condition that affects the anterior lobe of the pituitary gland - usually resulting in a partial or complete loss of functioning of that lobe.
When adrenal glands produce excessive amounts of certain hormones, they are called "overactive."
Although rare, most pituitary tumors are not cancerous (benign), comprising only 7 percent of brain tumors. However, most pituitary tumors will press against the optic nerves, causing vision problems.
Addison's disease is the result of an underactive adrenal gland.
Neuroendocrine and Pituitary Clinical Center
If you are a new patient at Massachusetts General Hospital, please begin the appointment process by calling the Mass General Registration and Referral Center at 866-211-6588 to register and obtain a unique Mass General Medical Record Number (MRN). The center is open Monday through Thursday, 8:00 am to 6:00 pm, and on Friday from 8:00 am to 5:00 pm.
Once you have your MRN, call 617-726-7948 to schedule an outpatient visit.
Inpatient consultations can be arranged by calling 617-726-7948.
Consult our appointments page for details about what to bring to your appointment. Please call us in advance of your appointment of you have any questions.
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