Recent publications from the Epilepsy Service faculty report on presurgical evaluation methods, new findings in seizure characterization, and evaluation of cortical architecture in MTLE.

Daniel Hoch, MD | Elizabeth Thiele, MD | Sydney Cash, MD

Epilepsy Service Publications - Andrew Cole, MD

  1. Karakis I, Velez-Ruiz N, Pathmanathan JS, Sheth SA, Eskandar EN, Cole AJ. Foramen ovale electrodes in the evaluation of epilepsy surgery: Conventional and unconventional uses.
    Epilepsy Behav. 2011 Jul 20 [Epub ahead of print]
    PMID:21782522. (PDF, 3008 KB)
  2. Dibbens LM, Karakis I, Bayly MA, Costello DJ, Cole AJ, Berkovic SF. Mutation of SCARB2 in a patient with progressive myoclonus epilepsy and demyelinating peripheral neuropathy.
    Arch Neurol. 2011 Jun;68(6):812-3.
    PMID: 21670406 (PDF, 100 KB)
  3. San-Juan D, Mayorga AP, Anschel DJ, Avellán AM, González-Aragón MF, Cole AJ. The double generalization phenomenon in juvenile absence epilepsy.
    Epilepsy Behav. 2011 Jul;21(3):318-20. Epub 2011 May 14.
    PMID: 21571594 (PDF, 963 KB)
  4. Karakis I, Cole AJ, Hoch DB, Sharma N. Extrapyramidal epilepsy.
    Epileptic Disord. 2011 Jun;13(2):181-4.
    PMID: 21561840, (PDF, 116 KB)
  5. Sims KB, Cole AJ, Sherman JC, Caruso PA, Snuderl M. Case records of the Massachusetts General Hospital. Case 8-2011. A 32-year-old woman with seizures and cognitive decline.
    N Engl J Med. 2011 Mar 17;364(11):1062-74.
    PMID: 21410375  (PDF, 1,240 KB)
  6. Cole AJ. Raymond Adams: A Life of Mind and Muscle. (Book review)
    Epilepsy & Behavior 19 (2010) 537. (PDF, 105 KB)
  7. Reinsberger C, Tanaka N, Cole AJ, Lee JW, Dworetzky BA, Bromfield EB, Hamiwka L, Bourgeois BF, Golby AJ, Madsen JR, Stufflebeam SM. Current dipole orientation and distribution of epileptiform activity correlates with cortical thinning in left mesiotemporal epilepsy.
    Neuroimage. 2010 Oct 1;52(4):1238-42.
    PMID: 20472073 (PDF, 610 KB)
  8. Fiskerstrand T, H'mida-Ben Brahim D, Johansson S, M'zahem A, Haukanes BI, Drouot N, Zimmermann J, Cole AJ, Vedeler C, Bredrup C, Assoum M, Tazir M, Klockgether T, Hamri A, Steen VM, Boman H, Bindoff LA, Koenig M, Knappskog PM. Mutations in ABHD12 cause the neurodegenerative disease PHARC: An inborn error of endocannabinoid metabolism. Am J Hum Genet. 2010 Sep 10;87(3):410-7.
    PMID: 20797687 [PubMed - indexed for MEDLINE] (PDF, 323 KB)
  9. Miller JW, Cole AJ. Is it necessary to define the ictal onset zone with EEG prior to performing epilepsy surgery?
    Epilepsy Behav. 2010 Sep 29. [Epub ahead of print]
    PMID: 20888304 (PDF, 140 KB)
  10. San-Juan D, Chiappa KH, Cole AJ. Propofol and the electroencephalogram.
    Clin Neurophysiol. 2010 Jan 11. [Epub ahead of print]
    PMID: 20071229 [PubMed - as supplied by publisher] (PDF, 743 KB)
  11. Zheng Y, Moussally J, Cash SS, Karnam HB, Cole AJ. Intravenous levetiracetam in the rat pilocarpine-induced status epilepticus model: Behavioral, physiological and histological studies.
    Neuropharmacology. 2009 Dec 21. [Epub ahead of print]
    PMID: 20026136 [PubMed - as supplied by publisher] (PDF, 901 KB)
  12. Orta DS, Chiappa KH, Quiroz AZ, Costello DJ, Cole AJ. Prognostic implications of periodic epileptiform discharges.
    Arch Neurol. 2009 Aug;66(8):985-91.
    PMID: 19667220 [PubMed - indexed for MEDLINE] (PDF, 86 KB)
  13. Tanaka N, Cole AJ, von Pechmann D, Wakeman DG, Hämäläinen MS, Liu H, Madsen JR, Bourgeois BF, Stufflebeam SM. Dynamic statistical parametric mapping for analyzing ictal magnetoencephalographic spikes in patients with intractable frontal lobe epilepsy.
    Epilepsy Res. 2009 Aug;85(2-3):279-86. Epub 2009 Apr 24.
    PMID: 19394198 [PubMed - indexed for MEDLINE] (PDF, 1358 KB)
  14. Löscher W, Cole AJ, McLean MJ. Commentary: physical approaches for the treatment of epilepsy: electrical and magnetic stimulation and cooling.
    Neurotherapeutics. 2009 Apr;6(2):258-62. Review.
    PMID: 19332318 [PubMed - indexed for MEDLINE] (PDF, 81 KB)
  15. San-Juan OD, Chiappa KH, Costello DJ, Cole AJ. Periodic epileptiform discharges in hypoxic encephalopathy: BiPLEDs and GPEDs as a poor prognosis for survival.
    Seizure. 2009 Jun;18(5):365-8. Epub 2009 Feb 4.
    PMID: 19196524 [PubMed - indexed for MEDLINE] (PDF, 786 KB)
  16. Cole AJ, Wiebe S. Debate: Should antiepileptic drugs be stopped after successful epilepsy surgery?
    Epilepsia. 2008 Dec;49 Suppl 9:29-34.
    PMID: 19087115 [PubMed - indexed for MEDLINE] (PDF, 76 KB)
  17. Costello DJ, Shields DC, Cash SS, Eskandar EN, Cosgrove GR, Cole AJ. Consideration of epilepsy surgery in adults should be independent of age.
    Clin Neurol Neurosurg. 2009 Apr;111(3):240-5. Epub 2008 Nov 22.
    PMID: 19028008 [PubMed - indexed for MEDLINE] (PDF, 240 KB)
  18. Costello DJ, Kilbride RD, Cole AJ. Cryptogenic New Onset Refractory Status Epilepticus (NORSE) in adults-Infectious or not?
    J Neurol Sci. 2009 Feb 15;277(1-2):26-31. Epub 2008 Nov 17.
    PMID: 19013586 [PubMed - indexed for MEDLINE] (PDF, 423 KB)
  19. Costello DJ, Cole AJ. Treatment of acute seizures and status epilepticus.
    J Intensive Care Med. 2007 Nov-Dec;22(6):319-47. Review.
    PMID: 18048876 [PubMed - indexed for MEDLINE] (PDF 2000 KB)
  20. Leeman BA, Cole AJ. Advancements in the Treatment of Epilepsy. Annu Rev Med. 2007 Sep 20; [Epub ahead of print]
    PMID: 17883367 [PubMed - as supplied by publisher] (PDF 152 KB)
  21. Cole AJ. Hippocampal Sclerosis: An inflammatory hypothesis. Neurology 2007 Sept 18;69:1204-1205. (PDF 209 KB)
  22. Cole AJ, Henson JW, Roehrl MH, Frosch MP. Case records of the Massachusetts General Hospital. Case 24-2007. A 20-year-old pregnant woman with altered mental status.
    N Engl J Med. 2007 Aug 9;357(6):589-600. No abstract available.
    PMID: 17687135 [PubMed - indexed for MEDLINE] (PDF 660 KB)
  23. Besio WG, Koka K, Cole AJ. Effects of Noninvasive Transcutaneous Electrical Stimulation via Concentric Ring Electrodes on Pilocarpine-induced Status Epilepticus in Rats.
    Epilepsia. 2007 Jul 25; [Epub ahead of print]
    PMID: 17651415 (PDF 168 KB)
  24. Leach NT, Sun Y, Michaud S, Zheng Y, Ligon KL, Ligon AH, Sander T, Korf BR, Lu W, Harris DJ, Gusella JF, Maas RL, Quade BJ, Cole AJ, Kelz MB, Morton CC. Disruption of diacylglycerol kinase delta (DGKD) associated with seizures in humans and mice.
    Am J Hum Genet. 2007 Apr;80(4):792-9. Epub 2007 Feb 12.
    PMID: 17357084 (PDF, 491 KB)
  25. Cole AJ. New screening tool for identifying major depression in patients with epilepsy.
    Nat Clin Pract Neurol. 2006 Dec;2(12):656-7. No abstract available.
    PMID: 17117168 (PDF, 79 KB)
  26. Costello DJ, Simon MV, Eskandar EN, Frosch MP, Henninger HL, Chiappa KH, Cole AJ.
    Efficacy of surgical treatment of de novo, adult-onset, cryptogenic, refractory focal status epilepticus.
    Arch Neurol. 2006 Jun;63(6):895-901.
    PMID: 16769873 (PDF, 1743 KB)
  27. Knake S, Halgren E, Shiraishi H, Hara K, Hamer HM, Grant PE, Carr VA, Foxe D, Camposano S, Busa E, Witzel T, Hamalainen MS, Ahlfors SP, Bromfield EB, Black PM, Bourgeois BF, Cole AJ, Cosgrove GR, Dworetzky BA, Madsen JR, Larsson PG, Schomer DL, Thiele EA, Dale AM, Rosen BR, Stufflebeam SM.
    The value of multichannel MEG and EEG in the presurgical evaluation of 70 epilepsy patients.
    Epilepsy Res. 2006 Apr;69(1):80-86. Epub 2006 Mar 3.
    PMID: 16516443 (PDF, 117 KB)
  28. Koh S, Santos TC, Cole AJ.
    Susceptibility to seizure-induced injury and acquired microencephaly following intraventricular injection of saporin-conjugated 192 IgG in developing rat brain.
    Exp Neurol. 2005 Aug;194(2):457-66.
    PMID: 16022871 (PDF, 580 KB)
  29. Brisman JL, Cosgrove GR, Thornton AF, Beer T, Bradley-Moore M, Shay CT, Hedley-Whyte ET, Cole AJ.
    Hyperacute neuropathological findings after proton beam radiosurgery of the rat hippocampus.
    Neurosurgery. 2005 Jun;56(6):1330-7; discussion 1337-8.
    PMID: 15918950 [PubMed - in process] (PDF, 1590 KB)
  30. Rabinov JD, Brisman JL, Cole AJ, Lee PL, Bussiere MR, Chapman PH, Loeffler JS, Cosgrove GR, Chaves T, Gonzalez RG.
    MRI Changes in the Rat Hippocampus following Proton Radiosurgery.
    Stereotact Funct Neurosurg. 2004 Oct 19;82(4):156-164
    PMID: 15499227 [PubMed - as supplied by publisher]
  31. Cole AJ.
    Status epilepticus and periictal imaging.
    Epilepsia. 2004;45 Suppl 4:72-7.
    PMID: 15281962 (PDF, 306 KB)
  32. Doherty CP, Cole AJ, Grant PE, Fischman A, Dooling E, Hoch DB, White TH, Cosgrove GR.
    Multimodal longitudinal imaging of focal status epilepticus.
    Can J Neurol Sci. 2004 May;31(2):276-81.
    PMID: 15198460 [PubMed - indexed for MEDLINE] (PDF, 1550 KB)
  33. Oster J, Doherty C, Grant PE, Simon M, Cole AJ.
    Diffusion-weighted imaging abnormalities in the splenium after seizures.
    Epilepsia. 2003 Jun;44(6):852-4.
    PMID: 12790901 (PDF, 799 KB)
  34. Brisman JL, Cole AJ, Cosgrove GR, Thornton AF, Rabinov J, Bussiere M, Bradley-Moore M, Hedley-Whyte T, Chapman PH.
    Radiosurgery of the rat hippocampus: magnetic resonance imaging, neurophysiological, histological, and behavioral studies.
    Neurosurgery. 2003 Oct;53(4):951-61.
    PMID: 14519227 [PubMed - indexed for MEDLINE] (PDF, 3847 KB)
  35. Cole AJ.
    Evaluation and treatment of epilepsy in multiply handicapped individuals.
    Epilepsy & behavior : E&B.. 2002 Dec;3(6S1):2-6.
    PMID: 12609305 [PubMed - as supplied by publisher] (HTML)  (PDF, 118 KB)
  36. Cole AJ, Dichter M.
    Neuroprotection and antiepileptogenesis: Overview, definitions, and context.
    Neurology. 2002 Nov 12;59(9 Suppl 5):S1-S2. No abstract available.
    PMID: 12428024 [PubMed - as supplied by publisher] (HTML)
  37. Dichter MA, Cole AJ.
    Neuroprotection and antiepileptogenesis: Where are we now?
    Neurology. 2002 Nov 12;59(9 Suppl 5):S36-S38. No abstract available.
    PMID: 12428031 [PubMed - as supplied by publisher] (HTML)
  38. Cole AJ, Koh S, Zheng Y.
    Are seizures harmful: what can we learn from animal models?
    Prog Brain Res. 2002;135:13-23. Review.
    PMID: 12143335 [PubMed - indexed for MEDLINE] (PDF, 464 KB)
  39. Brisman JL, Cosgrove GR, Cole AJ.
    Phosphorylation of P42/P44 MAP kinase and DNA fragmentation in the rat perforant
    pathway stimulation model of limbic epilepsy.
    Brain Res. 2002 Apr 12;933(1):50-9. (PDF, 1590 KB)
  40. Doherty CP, Hoch D, Cole AJ.
    Surgery for temporal-lobe epilepsy.
    N Engl J Med. 2002 Jan 24;346(4):292-5.
  41. Sheen VL, Dixon PH, Fox JW, Hong SE, Kinton L, Sisodiya SM, Duncan JS, Dubeau F, Scheffer IE, Schachter SC, Wilner A, Henchy R, Crino P, Kamuro K, DiMario F, Berg M, Kuzniecky R, Cole AJ, Bromfield E, Biber M, Schomer D, Wheless J, Silver K, Mochida GH, Berkovic SF, Andermann F, Andermann E, Dobyns WB, Wood NW, Walsh CA.
    Mutations in the X-linked filamin 1 gene cause periventricular nodular heterotopia in males as well as in females.
    Hum Mol Genet. 2001 Aug 15;10(17):1775-83. (PDF, 503 KB)
  42. Doherty CP, Cole AJ.
    The requirement for ictal EEG recordings prior to temporal lobe epilepsy surgery.
    Arch Neurol. 2001 Apr;58(4):678-80.
  43. Cole AJ.
    Is epilepsy a progressive disease? The neurobiological consequences of epilepsy.
    Epilepsia. 2000;41 Suppl 2:S13-22.
  44. Tanabe SM, Grant PE, Cosgrove GR, Hoch DB and Cole AJ. Delayed diagnosis of lesional epilepsy: Utility of modern imaging. Neurology and Clinical Neurophysiology, 2000 Article 1A:1-8.
  45. Koh S, Storey TW, Santos TC, Mian AY, Cole AJ.
    Early-life seizures in rats increase susceptibility to seizure-induced brain injury in adulthood.
    Neurology. 1999 Sep 22;53(5):915-21. (PDF, 326 KB)
  46. Wiederin TBJ, Chiappa KH, Krings T, Cuffin BN, Hoch DB, Cole AJ and Cosgrove GR. The utilitity of dipole source analysis of seizure onsets in the localization of epileptogenic zones as assessed by postsurgical outcome. Contemporary Neurology, 1999 Article 1A:2-10.
  47. Mendola JD, Rizzo JF 3rd, Cosgrove GR, Cole AJ, Black P, Corkin S.
    Visual discrimination after anterior temporal lobectomy in humans.
    Neurology. 1999 Mar 23;52(5):1028-37. (PDF, 372 KB)
  48. Hu RQ, Koh S, Torgerson T, Cole AJ.
    Neuronal stress and injury in C57/BL mice after systemic kainic acid administration.
    Brain Res. 1998 Nov 9;810(1-2):229-40.
  49. Murray B, Alessandrini A, Cole AJ, Yee AG, Furshpan EJ.
    Inhibition of the p44/42 MAP kinase pathway protects hippocampal neurons in a cell-culture model of seizure activity.
    Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):11975-80. (PDF, 354 KB)
  50. Tatum WO 4th, Ross J, Cole AJ.
    Epileptic pseudodementia.
    Neurology. 1998 May;50(5):1472-5. (HTML) (PDF)
  51. Weiss S, Cataltepe O, Cole AJ.
    Anatomical studies of DNA fragmentation in rat brain after systemic kainate
    Neuroscience. 1996 Sep;74(2):541-51. (PDF, 279 KB)
  52. Benson RR, Logan WJ, Cosgrove GR, Cole AJ, Jiang H, LeSueur LL, Buchbinder
    BR, Rosen BR, Caviness VS Jr.
    Functional MRI localization of language in a 9-year-old child.
    Can J Neurol Sci. 1996 Aug;23(3):213-9.
  53. Bhat RV, Cole AJ, Baraban JM.
    Chronic cocaine treatment suppresses basal expression of zif268 in rat
    forebrain: in situ hybridization studies.
    J Pharmacol Exp Ther. 1992 Oct;263(1):343-9.
  54. Bhat RV, Cole AJ, Baraban JM.
    Role of monoamine systems in activation of zif268 by cocaine.
    J Psychiatry Neurosci. 1992 Sep;17(3):94-102. Review.
  55. Cole AJ, Bhat RV, Patt C, Worley PF, Baraban JM.
    D1 dopamine receptor activation of multiple transcription factor genes in rat striatum.
    J Neurochem. 1992 Apr;58(4):1420-6. (PDF, 1496 KB)
  56. Bhat RV, Worley PF, Cole AJ, Baraban JM.
    Activation of the zinc finger encoding gene krox-20 in adult rat brain: comparison with zif268.
    Brain Res Mol Brain Res. 1992 Apr;13(3):263-6.
  57. Worley PF, Christy BA, Nakabeppu Y, Bhat RV, Cole AJ, Baraban JM.
    Constitutive expression of zif268 in neocortex is regulated by synaptic activity.
    Proc Natl Acad Sci U S A. 1991 Jun 15;88(12):5106-10. (PDF, 414 KB)
  58. Cole AJ, Abu-Shakra S, Saffen DW, Baraban JM, Worley PF.
    Rapid rise in transcription factor mRNAs in rat brain after electroshock-induced seizures.
    J Neurochem. 1990 Dec;55(6):1920-7.
  59. Cole AJ, Saffen DW, Baraban JM, Worley PF.
    Synaptic regulation of transcription factor mRNA in the rat hippocampus.
    Adv Neurol. 1990;51:103-8.
  60. Worley PF, Cole AJ, Murphy TH, Christy BA, Nakabeppu Y, Baraban JM.
    Synaptic regulation of immediate-early genes in brain.
    Cold Spring Harb Symp Quant Biol. 1990;55:213-23.
  61. Worley PF, Cole AJ, Saffen DW, Baraban JM.
    Regulation of immediate early genes in brain: role of NMDA receptor activation.
    Prog Brain Res. 1990;86:277-85.
  62. Cole AJ, Aubé M.
    Migraine with vasospasm and delayed intracerebral hemorrhage.
    Arch Neurol. 1990 Jan;47(1):53-6.
    PMID: 2294895 (PDF, 18 MB)
  63. Stratton KR, Cole AJ, Pritchett J, Eccles CU, Worley PF, Baraban JM.
    Intrahippocampal injection of pertussis toxin blocks adenosine suppression of synaptic responses.
    Brain Res. 1989 Aug 14;494(2):359-64.
  64. Cole AJ, Saffen DW, Baraban JM, Worley PF.
    Rapid increase of an immediate early gene messenger RNA in hippocampal neurons
    by synaptic NMDA receptor activation.
    Nature. 1989 Aug 10;340(6233):474-6. (PDF, 457 KB)
  65. Saffen DW, Cole AJ, Worley PF, Christy BA, Ryder K, Baraban JM.
    Convulsant-induced increase in transcription factor messenger RNAs in rat brain.
    Proc Natl Acad Sci U S A. 1988 Oct;85(20):7795-9. (PDF, 1960 KB)
  66. Cole AJ, Kuzniecky R, Karpati G, Carpenter S, Andermann E, Andermann F.
    Familial myopathy with changes resembling inclusion body myositis and periventricular leucoencephalopathy. A new syndrome.
    Brain. 1988 Oct;111 ( Pt 5):1025-37.
  67. Cole AJ, Andermann F, Taylor L, Olivier A, Rasmussen T, Robitaille Y, Spire JP.
    The Landau-Kleffner syndrome of acquired epileptic aphasia: unusual clinical outcome, surgical experience, and absence of encephalitis.
    Neurology. 1988 Jan;38(1):31-8.
  68. Cole AJ, Gloor P, Kaplan R.
    Transient global amnesia: the electroencephalogram at onset.
    Ann Neurol. 1987 Dec;22(6):771-2.

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