Teresa Gomez-Isla, MD

  • Lab Phone: 617-643-5562
  • Neurology Access Center: 1-855-644-6387

Research Investigator Profile

Teresa Gomez-Isla

Teresa Gomez-Isla, MD

  • Associate Professor,
    Harvard Medical School
  • Neurologist,
    Massachusetts General Hospital

 

 

Research Description

Dr. Gomez-Isla’s research includes basic science using transgenic mouse models of Alzheimer’s disease and dementia, analyzing data on clinical, neuroimaging and genetic features of demented patients and healthy controls.  She also manages multiple clinical trials.

Research interests Alzheimers, genetics, neuroimaging
Research techniques Neuroimaging, transgenic mouse models, clinical studies
Diseases studied Alzheimer's disease and other dementias
Selected publications
  1. Rapidly Progressive Dementia: Experience in a Tertiary Care Medical Center. Sala I, Marquié M, Sánchez-Saudinós MB, Sánchez-Valle R, Alcolea D, Gómez-Ansón B, Gómez-Isla T, Blesa R, Lleó A. Alzheimer Dis Assoc Disord. 2011 Oct 13. [Epub ahead of print]
  2. Activation of glycogen synthase kinase-3 beta mediates β-amyloid induced neuritic damage in Alzheimer's disease. DaRocha-Souto B, Coma M, Pérez-Nievas BG, Scotton TC, Siao M, Sánchez-Ferrer P, Hashimoto T, Fan Z, Hudry E, Barroeta I, Serenó L, Rodríguez M, Sánchez MB, Hyman BT, Gómez-Isla T. Neurobiol Dis. 2012 Jan;45(1):425-37. Epub 2011 Sep 13.
  3. Genetic cross-interaction between APOE and PRNP in sporadic Alzheimer's and Creutzfeldt-Jakob diseases. Calero O, Bullido MJ, Clarimón J, Frank-García A, Martínez-Martín P, Lleó A, Rey MJ, Rábano A, Blesa R, Gómez-Isla T, Valdivieso F, de Pedro-Cuesta J, Ferrer I, Calero M. PLoS One. 2011;6(7):e22090. Epub 2011 Jul 20.
  4. Reactive glia not only associates with plaques but also parallels tangles in Alzheimer's disease. Serrano-Pozo A, Mielke ML, Gómez-Isla T, Betensky RA, Growdon JH, Frosch MP, Hyman BT. Am J Pathol. 2011 Sep;179(3):1373-84. Epub 2011 Jul 21.
  5. Brain oligomeric β-amyloid but not total amyloid plaque burden correlates with neuronal loss and astrocyte inflammatory response in amyloid precursor protein/tau transgenic mice. DaRocha-Souto B, Scotton TC, Coma M, Serrano-Pozo A, Hashimoto T, Serenó L, Rodríguez M, Sánchez B, Hyman BT, Gómez-Isla T. J Neuropathol Exp Neurol. 2011 May;70(5):360-76.
NCBI PubMed link NCB I PubMed Publications
E-mail address tgomezisla@partners.org
Lab mailing address MassGeneral Institute for Neurodegenerative Disease
114 16th Street, 2-2008
Charlestown, MA 02129
Clinical interests Alzheimer's and dementias
Clinical mailing address Massachusetts General Hospital
Neurology, Suite 835
Wang Ambulatory Care Center
55 Fruit Street
Boston, MA 02114 USA
Clinical website address Memory Disorders Unit