Research Investigator Profile

Dr. Rosand

Jonathan Rosand, MD, MSc

Professor of Neurology, Harvard Medical School

Chief, Division of Neurocritical Care and Emergency Neurology

Medical Director, Neuroscience Intensive Care Unit, Massachusetts General Hospital


Faculty Member, Broad Institute of MIT and Harvard

Faculty Member, CHGR 


Research Description

To learn more about Dr. Rosand's research, please visit his lab website.

Research interests Ischemic Stroke, Hemorrhagic Stroke, White Matter Disease, Cerebral Amyloid Angiopathy, CADASIL, Traumatic Brain Injury 
Research techniques Genome-Wide Association Studies, Fine Mapping, Whole Exome Sequencing, , Gene Expression Analysis, Candidate Gene Studies, Neuroradiological Quantification of White Matter and Stroke Lesion Volumes
Diseases studied Ischemic Stroke, Hemorrhagic Stroke, Intracerebral Hemorrhage, White Matter Disease, Cerebral Amyloid Angiopathy, CAA, CADASIL
Selected publications
  1. Morotti A, Phuah CL, Anderson CD, Jessel MJ, Schwab K, Ayres AM, Pezzini A, Padovani A, Gurol ME, Viswanathan A, Greenberg SM, Goldstein JN, Rosand J. Leukocyte Count and Intracerebral Hemorrhage Expansion. Stroke; a journal of cerebral circulation. 2016; 47(6):1473-8. NIHMSID: NIHMS772971 PubMed [journal] PMID: 27103016, PMCID: PMC4879062
  2. Traylor M, Zhang CR, Adib-Samii P, Devan WJ, Parsons OE, Lanfranconi S, Gregory S, Cloonan L, Falcone GJ, Radmanesh F, Fitzpatrick K, Kanakis A, Barrick TR, Moynihan B, Lewis CM, Boncoraglio GB, Lemmens R, Thijs V, Sudlow C, Wardlaw J, Rothwell PM, Meschia JF, Worrall BB, Levi C, Bevan S, Furie KL, Dichgans M, Rosand J, Markus HS, Rost N. Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke. Neurology. 2016; 86(2):146-53. PubMed [journal] PMID: 26674333, PMCID: PMC4731688
  3. Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study. The Lancet. Neurology. 2015; NIHMSID: NIHMS750481 PubMed [journal] PMID: 26708676, PMCID: PMC4912948
  4. Biffi A, Anderson CD, Battey TW, Ayres AM, Greenberg SM, Viswanathan A, Rosand J. Association Between Blood Pressure Control and Risk of Recurrent Intracerebral Hemorrhage. JAMA. 2015; 314(9):904-12. NIHMSID: NIHMS751627 PubMed [journal] PMID: 26325559, PMCID: PMC4737594
  5. Brouwers HB, Battey TW, Musial HH, Ciura VA, Falcone GJ, Ayres AM, Vashkevich A, Schwab K, Viswanathan A, Anderson CD, Greenberg SM, Pomerantz SR, Ortiz CJ, Goldstein JN, Gonzalez RG, Rosand J, Romero JM. Rate of Contrast Extravasation on Computed Tomographic Angiography Predicts Hematoma Expansion and Mortality in
  6. Primary Intracerebral Hemorrhage. Stroke; a journal of cerebral circulation. 2015; 46(9):2498-503. NIHMSID: NIHMS706831 PubMed [journal] PMID: 26243220, PMCID: PMC4550492.
  7. Raffeld MR, Biffi A, Battey TW, Ayres AM, Viswanathan A, Greenberg SM, Rosand J, Anderson CD. APOE ε4 and lipid levels affect risk of recurrent nonlobar intracerebral hemorrhage. Neurology. 2015; 85(4):349-56. PubMed [journal] PMID: 26115730, PMCID: PMC4520812
NCBI PubMed link NCBI PubMed Publications
E-mail address
Lab mailing address Center for Human Genetic Research
185 Cambridge Street
Boston, MA 02114
Clinical interests NeuroCritical Care and Stroke
Clinical address Massachusetts General Hospital
Neurology, Suite 835
Wang Ambulatory Care Center
55 Fruit Street
Boston, MA 02114 USA
Clinical website address Stroke Service
Neuroscience Intensive Care Unit




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