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Lab Phone: 617-726-1262
Research Investigator Profile
Anne B. Young, MD, PhD
Dr. Young’s laboratory is examining the role of the protein alpha-synuclein, which plays a key role in the death of dopamine-producing brain cells in the Parkinson’s disease and other diseases with similar symptoms. Recently Dr. Young’s laboratory has examined the biology of synuclein in a group of Parkinson-like disorders, the Multiple Systems Atrophies. These studies suggest novel mechanisms in synuclein turnover, which may be relevant for treatments targeted at this protein.
In addition to her work in Parkinson’s disease, Dr. Young’s laboratory is attempting to elucidate cellular and systems mechanisms underlying the pathophysiology of Huntington’s disease. In an effort to help develop therapeutic targets for human movement disorders, she is conducting studies on the vulnerability of neurons to excitotoxic injury and the selective expression of glutamate receptors in these neurons.
Anne B. Young, MD, PhD (PDF)
MassGeneral Institute for Neurodegenerative DiseaseCNY B-114, Room 2006114 16th StreetCharlestown, MA 02129
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