Comprehensive Neurology Division

Part of the Neurology Department at Massachusetts General Hospital, the General Neurology Program’s board-certified neurologists work with primary care physicians to diagnose and treat a wide variety of neurological conditions.
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Comprehensive Neurology: 617-726-8639

About this Program

The Comprehensive Neurology Program was established in 2001 in response to patient demand for greater access to general neurology clinical services.

In recent years, medicine has been moving in the direction of increased specialization. Having a program devoted to comprehensive neurology unifies the efforts of our entire neurology department and represents yet another breakthrough in Massachusetts General Hospital's storied history.

Our board-certified neurologists, each of whom has subspecialty training, advise and consult with primary care physicians in diagnosing and treating a full range of neurological problems, including:

  • Weakness
  • Headaches of unusual types
  • Numbness
  • Tremor
  • Memory loss
  • Seizures

When further neurological care is required, we can make referrals to the appropriate specialist within the neurology department. Such conditions include:

  • Multiple sclerosis
  • Stroke
  • Migraine
  • Epilepsy
  • Alzheimer's disease
  • Parkinson's disease
  • Peripheral neuropathy
  • Myasthenia
  • Myopathy

A Tradition of General Neurology

General neurologists have always had a strong presence at Mass General. Raymond Adams, MD—the former chair of the neurology department and one of the founders of modern neurology—emphasized the importance of the comprehensive neurologist. Dr. Adams underscored the neurologist's ability to treat a wide variety of neurological problems, and his example continues to serve as our inspiration.

The General Neurology Program is headed by Director Nagagopal Venna, MD, whose subspecialties are multiple sclerosis and neuro-ophthalmology. The rest of our team's subspecialties are listed below:

  • David Chen, MD (headache)
  • Tracey Cho, MD (neuroinfectious disease)
  • Daniel Costello, MD (epilepsy)
  • James Lehrich, MD (spine diseases, multiple sclerosis)
  • David Margolin, MD, PhD (multiple sclerosis, neuroimmunology)
  • Shawn Murphy, MD, PhD (bioinformatics)
  • Stephen Parker, MD (neurotology)
  • Marie Pasinski, MD (community neurology)
  • Nagagopal Venna, MD (neurorheumatology, neuroinfectious disease)
  • Shirley Wray, MD, PhD (visual neurology)

Clinical Research Studies and Trials

The physicians in our program conduct clinical research studies and trials across a number of subspecialties. Patients have the opportunity to participate in these studies and trials and to potentially benefit from new therapies. For more information, please call the Comprehensive Neurology Program coordinator at 617-726-5533.

Conditions & Diseases

  • Alzheimer's Disease

    Alzheimer's disease is a progressive, neurodegenerative disease that occurs when nerve cells in the brain die, often resulting in symptoms such as impaired memory, thinking and behavior.

  • Epilepsy and Seizures

    Epilepsy is a neurological condition involving the brain that makes people more susceptible to having seizures.

  • Headache

    A headache is pain or discomfort in the head or face area.

  • Multiple Sclerosis

    Multiple sclerosis (MS) is a chronic disease of the central nervous system. It is thought to be an autoimmune disorder. It is an unpredictable condition that can be relatively benign, disabling, or devastating.

  • Muscular Contraction and Tension Headaches

    Tension headaches are the most common type of headache. Stress and muscle tension are often factors in tension type headaches.

  • Myasthenia Gravis

    Myasthenia gravis (MG) is a complex, autoimmune disorder in which antibodies destroy neuromuscular connections. This causes problems with the voluntary muscles of the body, especially the eyes, mouth, throat, and limbs.

  • Neurocutaneous Syndromes

    Neurocutaneous syndrome is a broad term for a group of neurologic disorders that can cause tumors to grow inside the brain, spinal cord, organs, skin and skeletal bones.

  • Parkinson's Disease

    Parkinson's disease (PD or, simply, Parkinson's) is a slowly progressing, degenerative disease that is associated with symptoms such as tremor or trembling of the arms, jaw, legs and face, stiffness or rigidity of the limbs and trunk, bradykinesia (slowness of movement), postural instability or impaired balance and coordination.

  • Stroke

    Stroke, also called brain attack, occurs when blood flow to the brain is disrupted.


Contact Us

General Neurology Program

Wang Ambulatory Care Center

15 Parkman Avenue, 7th Floor, Suite 720General Neurology Program Boston, MA 02114
  • Near Public Transit
  • Accessible
  • Phone: 617-726-8639

Mailing Address

General Neurology Program
Mailcode: WACC 7-720
Massachusetts General Hospital
55 Fruit Street
Boston, MA 02114

Access Patient Gateway Download referral form

Comprehensive Neurology: 617-726-8639

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