The Brain Trauma Lab is aimed at learning how to better treat the millions of children with brain trauma and similar problems, now and in the future.
The Brain Tumor Stem Cell Lab develops novel therapeutic strategies for glioblastoma through a better understanding of the biological and molecular characteristics of glioblastoma stem cells
Membrane proteins play critical roles in the brain. The Membrane Biology Lab studies ATP-hydrolyzing enzymes that control sodium, potassium and calcium movements. Molecular, cellular and biochemical approaches are used to study structure, function and physiology. Mutations found in human diseases, such as dystonia, are being studied in mutant mice.
Research in the Molecular Neurosurgery Lab focuses on the use of herpes simplex virus (HSV) vectors for cancer therapy and gene delivery in the nervous system, with the long-term goal being the therapeutic application of these vectors to patients.
The Multiple Sclerosis (MS) Imaging Laboratory in the Department of Neurology at Massachusetts General Hospital, led by Eric Klawiter, MD, Msc, is focused on developing new imaging techniques to better understand, diagnose and treat multiple sclerosis.
The Neural Prosthetic Lab seeks to improve the effectiveness of CNS-based neural prosthetics by understanding how and why neurons respond to electric stimulation. We use this knowledge to develop improved methods of stimulation. Projects focus on retinal prosthetics, DBS and other devices.
The Neuronal Communication and Restoration Lab probes the mechanisms by which individual neurons communicate locally and across cortical areas, and investigate new approaches for reconstituting the line of communication across areas disrupted within the CNS.
The Sensorimotor Integration Lab explores the influence of basal ganglia in adaptive learning and motor control in subjects undergoing surgery for movement disorders, such as Parkinson’s disease, while awake.
Research in the Translational Brain Tumor Immunology Lab focuses on the development and evaluation of novel therapies for brain tumors.
The Visual Prosthesis Lab is working to create a means to restore sight to the blind by sending signals from a digital camera directly into the brain.
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