Explore current research projects in the Department of Neurosurgery or search our open clinical trials and medical research studies.


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  • Brain Trauma Lab

    Brain Trauma Lab

    The Brain Trauma Lab is aimed at learning how to better treat the millions of children with brain trauma and similar problems, now and in the future.

  • Brain Tumor Stem Cell Lab

    Brain Tumor Stem Cell Lab

    The Brain Tumor Stem Cell Lab develops novel therapeutic strategies for glioblastoma through a better understanding of the biological and molecular characteristics of glioblastoma stem cells

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  • Membrane Biology Lab

    Membrane Biology Lab

    Membrane proteins play critical roles in the brain. The Membrane Biology Lab studies ATP-hydrolyzing enzymes that control sodium, potassium and calcium movements. Molecular, cellular and biochemical approaches are used to study structure, function and physiology. Mutations found in human diseases, such as dystonia, are being studied in mutant mice.

  • Molecular Neurosurgery Lab

    Molecular Neurosurgery Lab

    Research in the Molecular Neurosurgery Lab focuses on the use of herpes simplex virus (HSV) vectors for cancer therapy and gene delivery in the nervous system, with the long-term goal being the therapeutic application of these vectors to patients.

  • Multiple Sclerosis (MS) Imaging Laboratory

    MS Imaging Lab

    The Multiple Sclerosis (MS) Imaging Laboratory in the Department of Neurology at Massachusetts General Hospital, led by Eric Klawiter, MD, Msc, is focused on developing new imaging techniques to better understand, diagnose and treat multiple sclerosis.

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  • Neural Prosthetic Lab

    Neural Prosthetic Lab

    The Neural Prosthetic Lab seeks to improve the effectiveness of CNS-based neural prosthetics by understanding how and why neurons respond to electric stimulation. We use this knowledge to develop improved methods of stimulation. Projects focus on retinal prosthetics, DBS and other devices.

  • Neuronal Communication and Restoration Lab

    Neuronal Communication and Restoration Lab

    The Neuronal Communication and Restoration Lab probes the mechanisms by which individual neurons communicate locally and across cortical areas, and investigate new approaches for reconstituting the line of communication across areas disrupted within the CNS.

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  • Sensorimotor Integration Lab

    Sensorimotor Integration Lab

    The Sensorimotor Integration Lab explores the influence of basal ganglia in adaptive learning and motor control in subjects undergoing surgery for movement disorders, such as Parkinson’s disease, while awake.

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  • Visual Prosthesis Lab

    Visual Prosthesis Lab

    The Visual Prosthesis Lab is working to create a means to restore sight to the blind by sending signals from a digital camera directly into the brain.

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