Jan L. Shifren, M.D. is Associate Professor of Ob/Gyn and Reproductive Biology at Harvard Medical School, and a reproductive endocrinologist and Director of the Menopause Program in the Ob/Gyn Dept. at MGH. She attended Yale College and Harvard Medical School. She completed her residency in Ob/Gyn at BWH and MGH, and a fellowship in Reproductive Endocrinology and Infertility at UCSF. Dr. Shifren currently divides her time among research, teaching and patient care. Her clinical interests include caring for women with infertility, recurrent pregnancy loss, premature ovarian insufficiency, and concerns regarding menopause. She is an active member of the MGH Fertility Center, participating in the care of women requiring assisted reproductive technologies, including ovulation induction therapies and IVF. Her research focuses on menopause, including the effects of estrogens, androgens and alternative therapies on menopausal symptoms, mood, and sexual function. She has published numerous articles, abstracts, and book chapters and has delivered national and international presentations on menopause, hormone therapy, androgens for women, and female sexual function.
Dr. Shifren's research focuses on menopause, including the effects of estrogens, androgens and alternative therapies on menopausal symptoms, mood, and sexual function. Dr. Shifren has served as Principal Investigator and Co-Investigator for several important studies related to the menopause and female sexuality. She has published numerous articles, abstracts, and book chapters and has delivered national and international presentations on menopause, hormone therapy, androgens for women, and female sexual function.
Dr. Shifren is active in numerous professional societies, including the North American Menopause Society,American College of Obstetricians and Gynecologists, American Society of Reproductive Medicine, Society of Reproductive Endocrinologists, Endocrine Society, and Society for Gynecologic Investigation. She serves on the Editorial Boards of Menopause, Journal of Clinical Endocrinology and Metabolism, Ob.Gyn News, Menopausal Medicine, and the International Journal of Impotence Research. She is an ad hoc reviewer for Menopause, Fertility and Sterility, the New England Journal of Medicine, and the Journal of Clinical Endocrinology and Metabolism, among others.
Shifren JL, Braunstein GD, Simon JA, et al. Transdermal testosterone treatment in women with impaired sexual function after oophorectomy. N Engl J Med 2000; 343:682-8.Shifren JL, Ferrari, N. A better sex life. Newsweek 2004; 143 (19): 86-7.
Shifren JL, Davis SR, Moreau M, et al. Testosterone patch for the treatment of hypoactive sexual desire disorder in naturally menopausal women: results from the Intimate NM1 study. Menopause 2006; 13(5):770-9.
Shifren JL, Schiff I. Menopause. In: Berek JS, editor. Berek & Nova's Gynecology (Fourteenth Edition). Philadelphia: Lippincott Williams & Wilkins; 2007. p. 1323-40.
Shifren JL, Desindes S, McIlwain M, et al. A Randomized, open label, crossover study comparing the effects of transdermal vs. oral estrogen therapy on serum androgens, thyroid hormones, and adrenal hormones in naturally menopausal women. Menopause 2007;14(6):985-94.
Shifren JL, Monz BU, Russo PA, et al. Sexual problems and distress in United States women: prevalence and correlates. Obstet Gynecol 2008;112:970-8.