Physician Photo

Mark Steven Vrahas, MD

Robert W. Lovett Professor of Orthopedic Surgery, Harvard Medical School

Chair, Harvard Medical School Orthopaedic Trauma Initiative

Chief, Partners Orthopaedic Trauma Service

Dr. Vrahas is a leading specialist who treats orthopaedic injuries of the hip & pelvis. As Chief of the Partners Orthopaedic Trauma Service, Dr. Vrahas has created a care delivery system, ensuring patients receive optimal care during their recovery.

Department of Orthopaedics


  • MassGeneral Hospital for Children
  • Orthopaedics
  • Trauma Center
Clinical Interests
Orthopedic trauma
Total hip replacement
Hip fractures
Pelvic and acetabular fractures
Nonunions of fractures
Post traumatic reconstruction
Hip reconstruction/osteotomy
Boston: Massachusetts General Hospital
Medical Education
MD, University of Pittsburgh School of Medicine
Residency, University of Pittsburgh Medical Center
Fellowship, Sunnybrook & Women's College Health Sciences Centre
Fellowship, University of Iowa
Board Certifications
Orthopaedic Surgery, American Board of Orthopedic Surgery
Patient Age Group
Adult and pediatric
Accepting New Patients
Accepting New Patients


Dr. Vrahas was recruited to Boston in 1999 to develop an orthopaedic trauma program across Partners, which consists of Massachusetts General Hospital and Brigham and Women's Hospital. Dr. Vrahas' goals were to:
a. Meet and exceed the standards for clinical orthopaedic trauma care provided by major trauma centers around the county,
b. Develop an educational program for residents and fellows, and
c. Develop clinical and basic research programs
These efforts over Dr. Vrahas' tenure have led to a Trauma Program that is now nationally and internationally recognized for excellence.

Dr. Vrahas' clinical interests include pelvic and acetabular (hip socket) fracture fixation, fracture non union, and hip surgery. He is an internationally renowned pelvic and acetabular surgeon, who lectures frequently about this topic.


Dr. Vrahas is dedicated to understanding the human biological and clinical processes associated with traumatic orthopaedic injuries, and educating his peers and students. Toward this end, he has published prolifically on relevant topics like the cellular response to injury, the efficacy of certain orthopaedic implants and using gene therapy for fracture healing. Dr. Vrahas is very proud to have served as mentor to dozens of young orthopaedic residents and fellows interested in orthopaedics trauma surgery and research.


Select publications:

Thomas SH, Arthur AO, Howard Z, Shear ML, Kadzielski JL, Vrahas MS. Helicopter emergency medical services crew administration of antibiotics for open fractures. Air Med J. 2013;2:74-79.

Okike K, Lee OC, Makanji H, Harris MB, Vrahas MS. Factors associated with the decision for operative versus nonoperative treatment of displaced proximal humerus fractures in the elderly. Injury. 2013;4:448-455.

Menendez ME, Neuhaus V, Bot AG, Vrahas MS, Ring D. Do psychiatric comorbidities influence inpatient death, adverse events, and discharge after lower extremity fractures?. Clin Orthop. 2013;10:3336-3348.

Liu W, Zhou D, Liu F, Weaver MJ, Vrahas MS. Mechanical complications of intertrochanteric hip fractures treated with trochanteric femoral nails. J Trauma Acute Care Surg. 2013;2:304-310.

Ferreira E, Porter RM, Wehling N, O'Sullivan RP, Liu F, Boskey A, Estok DM, Harris MB, Vrahas MS, Evans CH, Wells JW. Inflammatory cytokines induce a unique mineralizing phenotype in mesenchymal stem cells derived from human bone marrow. J Biol Chem. 2013;41:29494-29505.

Fayaz HC, Haas N, Kellam J, Bavonratanavech S, Parvizi J, Dyer G, Pohlemann T, Jerosch J, Prommersberger KJ, Pape HC, Smith M, Vrahas M, Perka C, Siebenrock K, Elhassan B, Moran C, Jupiter JB. Improvement of research quality in the fields of orthopaedics and trauma: A global perspective. Int Orthop. 2013;7:1205-1212.

Departments collaborate to transform care for senior patients

Two MGH departments have joined together to redesign the way care is offered to senior patients with bone fractures.

Harvard Medical School welcomes the Harvard Medical School Orthopedic Trauma Initiative

The primary purpose of this Initiative is to foster collaboration amongst the orthopedic trauma services at all four Harvard-affiliated teaching hospitals in Boston: Beth Israel Deaconess Medical Center; Boston Children’s Hospital; Brigham and Women’s Hospital; and Massachusetts General Hospital.

Four New Professors of Harvard Medical School in Orthopaedic Surgery

Harvard Medical School promoted Francis J. Hornicek, MD, PhD, Orhun K. Muratoglu, PhD, David C. Ring, MD, PhD & Mark S. Vrahas, MD to professors of Orthopaedic Surgery.

Orthopaedic Associates
55 Fruit Street
Yawkey Center for Outpatient Care, Suite 3C
Boston, MA 02114-2696

Phone: 617-726-9111
Fax: 617-726-8214