Physician Photo

Santiago A. Lozano Calderon, MD, PhD

Orthopaedic Oncology Surgeon

Instructor in Orthopaedic Surgery, Harvard Medical School

Dr. Lozano specializes in the evaluation and treatment of primary benign and malignant tumors of bone and soft tissue, as well as metastatic bone disease. His practice involves clinical research evaluating treatment and outcomes in oncology patients.

Department of Orthopaedics


  • Cancer Center
  • Sarcoma and Connective Tissue Oncology
  • Osteosarcoma (Bone Cancer)
  • Multiple Myeloma
Clinical Interests
Benign bone tumors
Benign soft tissue tumors
Malignant bone tumors
Malignant soft tissue tumors
Metastatic bone disease
Bone infections
Metabolic bone disease
Multiple myeloma
Limb-sparing procedures
Boston: Massachusetts General Hospital
Medical Education
MD, Pontificia Universidad Javeriana Medical School
PhD, University of Amsterdam
Residency, New York Medical College at Westchester Medical Center
Foreign Languages
Patient Age Group
Accepting New Patients
Accepting New Patients


Dr. Lozano earned his MD from Pontificia Universidad Javeriana Medical School in Bogota, Colombia. Following his MD, he earned his PhD from the University of Amsterdam in the Netherlands. He conducted his PhD thesis research with Dr. Jesse Jupiter and Dr. David Ring at MGH. Dr. Lozano then completed his Orthopaedic Surgery Residency at New York Medical College in Valhalla, New York. He also completed a fellowship in Orthopaedic Oncology at MGH.


Dr. Lozano has a strong interest in clinical research in orthopaedic oncology. His academic practice involves multiple clinical studies evaluating particular neoplastic problems of osseous and connective tissue nature. His focus of research includes clinical outcomes after reconstructive oncologic surgery in the upper and lower extremities, oncologic problems in the upper extremity and functional outcomes after surgical treatment in patients with primary sarcomas of bone and soft-tissue, as well as metastatic bone disease.


Select publications:

Lozano Calderon SA. Surgical Treatment of Osteosarcoma of the Extremities. In: Choy E (ed). Osteosarcoma: Symptoms, Diagnosis and Treatment Options. First Edition. New York. Nova Science Publishers. New York, NY. 2014. p. 37-96

Lozano-Calderon SA, Colman MW, Raskin KA, Hornicek FJ, Gebhardt M. Use of Bisphosphonates in Orthopedic Surgery: Pearls and Pitfalls. Orthop Clin North Am. 2014 Jul;45(3):403-416.

Colman MW, Lozano-Calderon S, Raskin KA, Hornicek FJ, Gebhardt M. Non-neoplastic Soft Tissue Masses That Mimic Sarcoma. Orthop Clin North Am. 2014 Apr;45(2):245-255.

Teunis T, Nota SP, Hornicek FJ, Schwab JH, Lozano-Calderon SA. Outcome After Reconstruction of the Proximal Humerus for Tumor Resection: A Systematic Review. Clin Orthop Relat Res. 2014 Jan 28.

Lozano-Calderon SA, Kenan S. Total condylar unipolar expandable prosthesis for proximal tibia malignant bone tumors in early childhood. Orthopedics. 2011 Dec 6;34(12)

Lozano-Calderon SA, Shen J, Doumato DF, Greene DA, Zelicof SB. Cruciate-retaining vs posterior-substituting inserts in total knee arthroplasty: functional outcome comparison. J Arthroplasty. 2013 Feb;28(2):234-242.

Lozano Calderon SA, Shen J, Doumato DF, Zelicof S. Functional Outcomes in High-function-demand patients after total knee arthroplasty. Orthopedics. 2012 May;35(5):e681-90.

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Orthopaedic Associates
55 Fruit Street
Yawkey Center for Outpatient Care, Suite 3B
Boston, MA 02114-2696

Phone: 617-724-3700
Fax: 617-726-6823