Photo of Santiago A. Lozano Calderon, MD, PhD

Santiago A. Lozano Calderon, MD, PhD

  • Orthopaedic Oncology Surgeon
  • Instructor in Orthopaedic Surgery, Harvard Medical School


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Dr. Lozano specializes in the evaluation and treatment of primary benign and malignant tumors of bone and soft tissue, as well as metastatic bone disease. His practice involves clinical research evaluating treatment and outcomes in oncology patients.



Clinical Interests
  • Benign bone tumors
  • Benign soft tissue tumors
  • Malignant bone tumors
  • Malignant soft tissue tumors
  • Metastatic bone disease
  • Bone infections
  • Metabolic bone disease
  • Multiple myeloma
  • Sarcoma
  • Amputations
  • Limb-sparing procedures
Medical Education
  • MD, Pontificia Universidad Javeriana Medical School
  • PhD, University of Amsterdam
  • Residency, New York Medical College at Westchester Medical Center
  • Boston: Massachusetts General Hospital
Insurances Accepted
  • Aetna Health Inc.
  • Beech Street
  • Blue Cross Blue Shield - Blue Care 65
  • Blue Cross Blue Shield - Indemnity
  • Blue Cross Blue Shield - Managed Care
  • Blue Cross Blue Shield - Partners Plus
  • Centene/Celticare
  • Cigna (PAL #'s)
  • Fallon Community HealthCare
  • Great-West Healthcare (formally One Health Plan)
  • Harvard Pilgrim Health Plan - ACD
  • Harvard Pilgrim Health Plan - PBO
  • Health Care Value Management (HCVM)
  • Humana/Choice Care PPO
  • Medicaid
  • Medicare
  • Medicare - ACD
  • Neighborhood Health Plan - ACD
  • Neighborhood Health Plan - PBO
  • OSW - Connecticut
  • OSW - Maine
  • OSW - New Hampshire
  • OSW - Rhode Island
  • Private Health Care Systems (PHCS)
  • Senior Whole Health
  • TriCare
  • Tufts Health Plan
  • Unicare
  • United Healthcare (non-HMO) - ACD
  • United Healthcare (non-HMO) - PBO
Patient Age Group

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Dr. Lozano earned his MD from Pontificia Universidad Javeriana Medical School in Bogota, Colombia. Following his MD, he earned his PhD from the University of Amsterdam in the Netherlands. He conducted his PhD thesis research with Dr. Jesse Jupiter and Dr. David Ring at MGH. Dr. Lozano then completed his Orthopaedic Surgery Residency at New York Medical College in Valhalla, New York. He also completed a fellowship in Orthopaedic Oncology at MGH.

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Research & Publications

Research Summary

Dr. Lozano has a strong interest in clinical research in orthopaedic oncology. His academic practice involves multiple clinical studies evaluating particular neoplastic problems of osseous and connective tissue nature. His focus of research includes clinical outcomes after reconstructive oncologic surgery in the upper and lower extremities, oncologic problems in the upper extremity and functional outcomes after surgical treatment in patients with primary sarcomas of bone and soft-tissue, as well as metastatic bone disease.


Select publications:

Lozano Calderon SA. Surgical Treatment of Osteosarcoma of the Extremities. In: Choy E (ed). Osteosarcoma: Symptoms, Diagnosis and Treatment Options. First Edition. New York. Nova Science Publishers. New York, NY. 2014. p. 37-96

Lozano-Calderon SA, Colman MW, Raskin KA, Hornicek FJ, Gebhardt M. Use of Bisphosphonates in Orthopedic Surgery: Pearls and Pitfalls. Orthop Clin North Am. 2014 Jul;45(3):403-416.

Colman MW, Lozano-Calderon S, Raskin KA, Hornicek FJ, Gebhardt M. Non-neoplastic Soft Tissue Masses That Mimic Sarcoma. Orthop Clin North Am. 2014 Apr;45(2):245-255.

Teunis T, Nota SP, Hornicek FJ, Schwab JH, Lozano-Calderon SA. Outcome After Reconstruction of the Proximal Humerus for Tumor Resection: A Systematic Review. Clin Orthop Relat Res. 2014 Jan 28.

Lozano-Calderon SA, Kenan S. Total condylar unipolar expandable prosthesis for proximal tibia malignant bone tumors in early childhood. Orthopedics. 2011 Dec 6;34(12)

Lozano-Calderon SA, Shen J, Doumato DF, Greene DA, Zelicof SB. Cruciate-retaining vs posterior-substituting inserts in total knee arthroplasty: functional outcome comparison. J Arthroplasty. 2013 Feb;28(2):234-242.

Lozano Calderon SA, Shen J, Doumato DF, Zelicof S. Functional Outcomes in High-function-demand patients after total knee arthroplasty. Orthopedics. 2012 May;35(5):e681-90.

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Orthopaedic Associates
55 Fruit Street
Boston MA, 02114-2696
Phone: 617-724-3700
Fax: 617-726-6823

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