News about Massachusetts General Hospital Pathology research advances. CRISPR-Cas9 nucleases, RDW - a novel early-warning biomarker, and new computational pathology diagnostic modes.


Read more Pathology news coverage from Massachusetts General Hospital, and view Mass General news and information from newsletters, videos, Facebook, Twitter, Pintrest, and Flickr

Spring-Summer 2015 Mass General Magazine - MGH Pathology experts forge new mode of diagnosis
 06-22-15 Research team evolves CRISPR-Cas9 nucleases with novel properties
 06-22-15 Why we need to talk now about the brave new world of editing genes
 04-02-15 Effects of Red-Cell Storage Duration on Patients Undergoing Cardiac Surgery
 04-28-15 Faculty member Jeannie Lee, MD, PhD elected to National Academy of Science
 04-02-15 Modulation of red blood cell population dynamics is a fundamental homeostatic response to disease 

Decreased red blood cell clearance appears to predict development and worsening of serious diseases

 04-01-15 Steering Pathology Into the Future. MGH Pathology Experts Forge New Mode of Diagnosis 
 12-11-14 Tethered Capsule Endomicroscopy
 11-26-14 Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes
 11-26-14 Clone Wars — The Emergence of Neoplastic Blood-Cell Clones with Aging

Genetic and epigenetic fine mapping of causal autoimmune disease variants - Nature publication - Bradley Bernstein, MD, PhD

 10-29-14 Researchers Map Overlap Between Causal SNPs and Regulatory Elements for Autoimmune Conditions - Bradley Bernstein, MD, PhD -
 10-9-2014 National Brain Tumor Society 2014 - David Louis receives Feldman Founder’s Award for outstanding contributions and invaluable impact on brain tumor researchis

MGH researchers chart cellular complexity of brain tumorsMario Suvà, MD, PhD

 09-27-13 On the Hunt - New survey of DNA alterations could aid search for cancer genes
 03-5-13 Cancer detection as easy as popping a pill
 07-25-13 CRISPR/Cas Comes of Age – Almost – Genetic Engineering & Biotechnology News
 10-31-13 Evicting Leukemia - Bone drug kills resistant cancer stem cells by making home unlivable
 01-29-13 Joung lab demonstrates in vivo genome editing using CRISPR-Cas nucleases
 01-13-13 Pill-sized device provides rapid, detailed imaging of esophageal liningGary Tearney, MD, PhD
 01-10-13 Efficient genome editing in zebrafish using a CRISPR-Cas systemKeith Joung, MD, PhD
 11-00-12 Genome-editing tools storm ahead: The menu of maturing, diversifying methods calls for careful selections in experimental designKeith Joung, MD, PhD

NIH continues its commitment to high risk-high reward researchJohn Higgins, MD

 07-10-12 The challenges posed by cancer heterogeneityJohn Iafrate, MD, PhD
 04-13-12 Martin Prize for Basic Research awarded to Bradley Bernstein, MD, PhD
 04-09-12 Rapid method of assembling new gene-editing tool could revolutionize genetic research– Keith Joung, MD, PhD
 03-2-12 Innovative MGHers honored with Bowditch Prize– Anand Dighe, MD, PhD
 02-29-12 Science Translational Medicine -Sikel Cell Diagnostics - John Higgins, MD
 01-27-12 Systems Biology and Red Cells - John Higgins, MD
 12-28-11 Nature Method of the Year - Gene-editing nucleases (PDF) – Keith Joung, MD, PhD
 12-28-11 Method developed by MGH investigator chosen as Method of the Year by Nature Methods(video)— Keith Joung, MD, PhD

Combinatorial Patterning of Chromatin Regulators Uncovered by Genome-wide Location Analysis in Human Cells– Bradley Bernstein, MD, PhD

 12-01-11 Mass. General study finds amplification of multiple cell-growth genes in some brain tumors– John Iafrate, MD, PhD
 08-05-11 Targeted gene disruption in somatic zebrafish cells using engineered TALENs
 05-06-11 Three Pathology Faculty Receive 2011 MGH Research Scholars Awards

Epigenomic findings illuminate veiled variants - Bradley Bernstein, co-senior author

 03-22-11 In Vivo Systems Analysis Identifies Spatial and Temporal Aspects of the Modulation of TNF-α–Induced Apoptosis and Proliferation by MAPKs
 12-12-10 Joint MGH-SEAS study - Model of Red Blood Cells May Predict Anemia Risk

Molecular Diagnostics Provides Real-time Guidance for Novel ALK Inhibitor Treatment of Lung Cancers

 09-30-10 Keith Joung receives NIH Director’s Transformative Research Project Award


Keith Joung Receives Prestigious NIH Pioneer Award


Ion Torrent Announces Ion PGM Sequencer Grant Winners
 02-22-10 New Scan May Help Find Aggressive Prostate Tumors
 10-22-09 MGH to Test e-Pathologist System with NEC
 10-09-09 MGH Personalized Medicine Program Covered in Science
 08-26-09 Sunquest, Partners HealthCare System and Massachusetts General Hospital Announce Agreement to Co-Develop Next Generation Diagnostic Pathology Solutions
 03-26-09 MGH Pathologist Becomes Howard Hughes Medical Institute Investigator
 03-02-09 Translational Oncology Diagnostic Initiative Gets Started
 07-24-08 Engineering Customized Zinc-Finger Nucleases
 2007 Genome-Wide Chromatin Maps for Embryonic Stem Cells
 2007 New WHO Classification of CNS Tumors