News about Massachusetts General Hospital Pathology research advances. CRISPR-Cas9 nucleases, RDW - a novel early-warning biomarker, and new computational pathology diagnostic modes.

 

Read more Pathology news coverage from Massachusetts General Hospital, and view Mass General news and information from newsletters, videos, Facebook, Twitter, Pintrest, and Flickr

   
Spring-Summer 2015 Mass General Magazine - MGH Pathology experts forge new mode of diagnosis
   
 06-22-15 Research team evolves CRISPR-Cas9 nucleases with novel properties
   
 06-22-15 Why we need to talk now about the brave new world of editing genes
   
 04-02-15 Effects of Red-Cell Storage Duration on Patients Undergoing Cardiac Surgery
   
 04-28-15 Faculty member Jeannie Lee, MD, PhD elected to National Academy of Science
   
 04-02-15 Modulation of red blood cell population dynamics is a fundamental homeostatic response to disease 
   
 04-02-15

Decreased red blood cell clearance appears to predict development and worsening of serious diseases

   
 04-01-15 Steering Pathology Into the Future. MGH Pathology Experts Forge New Mode of Diagnosis 
   
 12-11-14 Tethered Capsule Endomicroscopy
   
 11-26-14 Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes
   
 11-26-14 Clone Wars — The Emergence of Neoplastic Blood-Cell Clones with Aging
   
 10-29-14

Genetic and epigenetic fine mapping of causal autoimmune disease variants - Nature publication - Bradley Bernstein, MD, PhD

   
 10-29-14 Researchers Map Overlap Between Causal SNPs and Regulatory Elements for Autoimmune Conditions - Bradley Bernstein, MD, PhD - Genomeweb.com
   
 10-9-2014 National Brain Tumor Society 2014 - David Louis receives Feldman Founder’s Award for outstanding contributions and invaluable impact on brain tumor researchis
   
 06-16-14

MGH researchers chart cellular complexity of brain tumorsMario Suvà, MD, PhD

   
 09-27-13 On the Hunt - New survey of DNA alterations could aid search for cancer genes
   
 03-5-13 Cancer detection as easy as popping a pill
   
 07-25-13 CRISPR/Cas Comes of Age – Almost – Genetic Engineering & Biotechnology News
   
 10-31-13 Evicting Leukemia - Bone drug kills resistant cancer stem cells by making home unlivable
   
 01-29-13 Joung lab demonstrates in vivo genome editing using CRISPR-Cas nucleases
   
 01-13-13 Pill-sized device provides rapid, detailed imaging of esophageal liningGary Tearney, MD, PhD
   
 01-10-13 Efficient genome editing in zebrafish using a CRISPR-Cas systemKeith Joung, MD, PhD
   
 11-00-12 Genome-editing tools storm ahead: The menu of maturing, diversifying methods calls for careful selections in experimental designKeith Joung, MD, PhD
   
 09-17-12

NIH continues its commitment to high risk-high reward researchJohn Higgins, MD

   
 07-10-12 The challenges posed by cancer heterogeneityJohn Iafrate, MD, PhD
   
 04-13-12 Martin Prize for Basic Research awarded to Bradley Bernstein, MD, PhD
   
 04-09-12 Rapid method of assembling new gene-editing tool could revolutionize genetic research– Keith Joung, MD, PhD
   
 03-2-12 Innovative MGHers honored with Bowditch Prize– Anand Dighe, MD, PhD
   
 02-29-12 Science Translational Medicine -Sikel Cell Diagnostics - John Higgins, MD
   
 01-27-12 Systems Biology and Red Cells - John Higgins, MD
   
 12-28-11 Nature Method of the Year - Gene-editing nucleases (PDF) – Keith Joung, MD, PhD
   
 12-28-11 Method developed by MGH investigator chosen as Method of the Year by Nature Methods(video)— Keith Joung, MD, PhD
   
 12-23-11

Combinatorial Patterning of Chromatin Regulators Uncovered by Genome-wide Location Analysis in Human Cells– Bradley Bernstein, MD, PhD

   
 12-01-11 Mass. General study finds amplification of multiple cell-growth genes in some brain tumors– John Iafrate, MD, PhD
   
 08-05-11 Targeted gene disruption in somatic zebrafish cells using engineered TALENs
   
 05-06-11 Three Pathology Faculty Receive 2011 MGH Research Scholars Awards
   
 03-23-11

Epigenomic findings illuminate veiled variants - Bradley Bernstein, co-senior author

   
 03-22-11 In Vivo Systems Analysis Identifies Spatial and Temporal Aspects of the Modulation of TNF-α–Induced Apoptosis and Proliferation by MAPKs
 
 12-12-10 Joint MGH-SEAS study - Model of Red Blood Cells May Predict Anemia Risk
   
 10-27-10

Molecular Diagnostics Provides Real-time Guidance for Novel ALK Inhibitor Treatment of Lung Cancers

   
 09-30-10 Keith Joung receives NIH Director’s Transformative Research Project Award
   

 09-03-10

Keith Joung Receives Prestigious NIH Pioneer Award
   

 04-29-10

Ion Torrent Announces Ion PGM Sequencer Grant Winners
   
 02-22-10 New Scan May Help Find Aggressive Prostate Tumors
   
 10-22-09 MGH to Test e-Pathologist System with NEC
   
 10-09-09 MGH Personalized Medicine Program Covered in Science
   
 08-26-09 Sunquest, Partners HealthCare System and Massachusetts General Hospital Announce Agreement to Co-Develop Next Generation Diagnostic Pathology Solutions
   
 03-26-09 MGH Pathologist Becomes Howard Hughes Medical Institute Investigator
   
 03-02-09 Translational Oncology Diagnostic Initiative Gets Started
   
 07-24-08 Engineering Customized Zinc-Finger Nucleases
   
 2007 Genome-Wide Chromatin Maps for Embryonic Stem Cells
   
 2007 New WHO Classification of CNS Tumors