Massachusetts General Hospital

Biography

Associate Professor of Pathology
Harvard Medical School

Dr. Sgroi is an Associate Professor of Pathology at Harvard Medical School, the Director of Breast Pathology and a Member and Principal Investigator in the Division of Molecular Pathology Research and Center for Cancer Research at the Massachusetts General Hospital.  Dr Sgroi received his undergraduate degree from Bowdoin College and his medical degree from the University of Connecticut School of Medicine.  After completing a residency in anatomic pathology at Massachusetts General Hospital, Dr Sgroi completed a postdoctoral research fellowship in molecular pathology under the direction of Dr. Ivan Stamenkovic at Massachusetts General Hospital. His laboratory investigates the molecular genetic basis of human breast cancer and has utilized gene expression and proteomic technologies to better understand breast cancer progression. Dr Sgroi has shown that gene expression alterations are powerful predictors of breast cancer outcome and therapeutic response. His laboratory is currently focusing on determining the clinical utility of the HOXB13:IL17BR and MGI biomarkers in estrogen receptor-positive,lymph node negative breast cancer patients, and understanding the molecular functional role of HOXB13 and IL17BR as it relates to anti-hormonal therapeutic response.

ResearchHuman Breast Cancer Anti-Hormonal Resistance

See details at the Sgroi Lab.

PublicationsBibliography of Dennis C. Sgroi via PubMed