Massachusetts General Hospital

Biography

Clinical Associate in Pathology
Massachusetts General Hospital

Henry Willard Williams Professor
of Ophthamology, Emeritus
Harvard Medical School

Director, David Glendenning Cogan Laboratory of Ophthalmic Pathology

Email: fjakobiec@partners.org

Research

Focus has been on ophthalmic oncology and the characterization of ocular and adnexal (conjunctiva, eyelids, and orbital soft tissue and bones) inflammations and tumors. Main ophthalmic pathologic probes have consisted of light and transmission electron microscopy and immunoperoxidase staining. Pre-malignant and malignant conjunctival melanocytic disorders (so-called primary acquired melanosis) have been intensively studied. Clinicopathologic series with immunologic investigations have been employed in the study of lympho-proliferations of the ocular adnexa. Finally, idiopathic orbital inflammations (pseudotumors) and Wegener's granulomatosis have been subjected to more rigorous clinicopathologic diagnostic criteria.

PublicationsBibliography of Frederick Jakobiec via PubMed