Research

Funded research by Pathology Service faculty is divided among a number of different laboratories and departments. Pathology Research activities occupy approximately 20,000 square feet within Pathology, with Pathology researchers receiving approximately $7.5 million dollars in direct costs of annual research support.

The major Pathology research laboratories are the Molecular Pathology Laboratory on CNY7 and CNY6 (Drs. David Louis, Brad Bernstein, Kevin Haigis, Keith Joung, Gayatry Mohapatra, Cathy Nutt, Sandra Orsulic, Eveline Schneeberger, Dennis Sgroi and Anat Stemmer-Rachamimov), Experimental Pathology on Simches 8 (Drs. Atul Bhan, Atsushi Mizoguchi and Jim Stone) and Immunopathology Research (Drs. Robert Colvin and R. Neal Smith). The largest Unit, Molecular Pathology, is led by Dr. J. Keith Joung.  In addition, extensive translational research is performed by the Diagnostic Molecular Pathology Laboratory, led by Dr. A. John Iafrate.

Multiple Pathology faculty have funded laboratory research efforts that occupy space in other departments: Dr. Matthew Frosch (Neurology); Dr. Gary Tearney (Dermatology and Wellman Photomedicine); Dr. Drucilla Roberts (Pediatric Surgery); Dr. Lawrence Zukerberg (Vincent Gynecology); Dr. Chin-Lee Wu (Urology); Dr. Fred Preffer (Center for Regenerative Medicine & Technology); Dr. Kamran Badizadegan (George Harrison Spectroscopy Lab, MIT); and Dr. Leo Cheng (Radiology). In addition, most Pathology Service staff are involved in diverse clinicopathological research activities.

The Research Division works with all Units of the Pathology Service to foster its research mission. Activities include a popular, weekly pan-departmental Molecular Pathology and Research (MPR) conference, a pathology research mentoring program for residents, and an NIH Training Grant that supports 7 fellows per year. The Division oversees a number of core facilities, including two laser capture microdissection apparatuses, a tissue microarrayer and an array comparative genomic hybridization core. The Division has also participated in an Affymetrix microarray facility at the adjacent MGH Cancer Center.