Photo of Jonathan Edward Alpert, MD, PhD

Jonathan Edward Alpert, MD, PhD

  • Associate Chief of Psychiatry for Clinical Services
  • Director, Depression Clinical and Research Program


Not Accepting New Patients




Clinical Interests
  • Major depressive disorder
  • Mood disorders
  • Anxiety disorders
  • Psychopharmacology
Medical Education
  • PhD, Cambridge University
  • MD, Yale University School of Medicine
  • Residency, Children's Hospital Boston|Residency, McLean Hospital
Board Certifications
  • Psychiatry
  • Boston: Massachusetts General Hospital
Insurances Accepted
  • Aetna Health Inc.
  • Beech Street
  • Blue Cross Blue Shield - Blue Care 65
  • Blue Cross Blue Shield - Indemnity
  • Blue Cross Blue Shield - Managed Care
  • Blue Cross Blue Shield - Partners Plus
  • Centene/Celticare
  • Great-West Healthcare (formally One Health Plan)
  • Health Care Value Management (HCVM)
  • Humana/Choice Care PPO
  • MassHealth
  • Medicare
  • Medicare - ACD
  • OSW - Maine
  • OSW - New Hampshire
  • Private Health Care Systems (PHCS)
  • Senior Whole Health
  • TriCare
  • Tufts Health Plan
  • Unicare
  • United Behavioral Health
  • United Behavioral Health - MGH
Patient Age Group

Edit Profile


Dr. Jonathan E. Alpert is Associate Chief of Psychiatry for Clinical Services at MGH as well as Director of the Depression Clinical and Research Program. He is an Associate Professor of Psychiatry and the first incumbent of the Joyce R. Tedlow Chair in the Field of Depression Studies at Harvard Medical School. 

He received his BA and MD from Yale University and his PhD in behavioral pharmacology from the University of Cambridge (UK), where he was a Marshall Scholar. He completed residencies at Boston Children's Hospital and at McLean Hospital before joining the MGH Department of Psychiatry in 1992.

Dr. Alpert is a Distinguished Fellow of the American Psychiatric Association and a member of the Association of Directors of Medical Student Education, Association for Academic Psychiatry and the Massachusetts Psychiatric Society. He serves on the board of the National Network of Depression Centers and the Scientific Advisory Council of the American Foundation for Suicide Prevention. He is a recipient of the Cynthia Kettyle Teaching Award from Harvard Medical School, the Psychopharmacology Supervision Awards from trainees of the MGH/McLean Adult Psychiatry Residency and the Clinical Mentorship Award from the MGH Department of Psychiatry. He has published over 180 original articles and chapters in the areas of depression research, clinical psychopharmacology, and medical education.

Edit Profile

Research & Publications

Research Summary

Dr. Alpert's research interests include innovative treatments for resistant depression, biomarkers and clinical predictors of drug response, and impact of early age of onset and of anxiety and other comorbid illness on course and treatment responsiveness of Major Depressive Disorder. He is also interested in research relating to medical education in psychiatry and to the ethical conduct of clinical trials..


View my most recent publications at PubMed

Edit Profile


Psychiatry-Outpatient Services
15 Parkman Street
Boston MA, 02114-3117
Phone: 617-726-5948617-724-5512
Fax: 617-726-7541
Depression Clinical and Research Program
One Bowdoin Square
6th Floor
Boston MA, 02114-2790
Phone: 617-726-8895

Edit Profile

Back to Top