Psychiatric & Neurodevelopmental Genetics Unit

The mission of PNGU is to identify and characterize the genetic basis of psychiatric, behavioral, and neurodevelopmental disorders and to translate these discoveries to improvements in clinical care and public health.

NAME Laramie Duncan, Ph.D. Research Fellow
Psychiatric and Neurodevelopmental Genetics Unit
Center for Human Genetic Research
Massachusetts General Hospital
Richard B. Simches Research Center
185 Cambridge Street
Boston, MA 02114
Phone: 617-643-9010
Email: Laramied@gmail.com

Laramie Duncan is a graduate of the University of Georgia (BS Environmental Sciences) and the University of Colorado at Boulder (joint PhD in Neuroscience and Clinical Psychology & Certificate in Behavioral Genetics). She is interested in identifying genetic variants underlying a class of related phenotypes: schizophrenia, bipolar disorder, psychosis, and mania, in the service of elucidating the etiology of these phenomena. She is particularly interested in multi-SNP/variant analyses and the use of statistical methods that evaluate measures of data other than the mean (for example, variance).

 

Publications:

  • Sheets, E. S., Duncan, L. E., Bjornsson, A. S., Craighead, L. W., & Craighead, W. E. (in press).  Personality pathology factors predict recurrent major depressive disorder in emerging adults. Journal of Clinical Psychology, xx(xx), xx-xx.
  • Duncan, L.E. (2013) Paying Attention to All Results, Positive and Negative. JAACAP - Journal of the American Academy of Child and Adolescent Psychiatry, 52(5), 462-465.
  • Anderson-Schmidt, H., Beltcheva, O., Brandon, M.D., Byrne, E.M., Diehl, E.J., Duncan, L., Gonzalez, S.D., et al. (2013). Selected rapporteur summaries from the XX world congress of psychiatric genetics, Hamburg, Germany, October 14–18, 2012. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 162(2) 96–121. doi:10.1002/ajmg.b.32132 
  • Duncan, L.E. (accepted 2012) Gene-Environment Interactions in Behavioral Genetics.  In S. Rhee, & A. Ronald (Eds.), Behavioral Genetics Book Series. New York, NY: Springer Publishing Company.
  • Duncan, L.E. & Keller, M.C. (2012) Response to Pluess and Belsky Letter. American Journal of Psychiatry,169(2), 223-223.
  • Duncan, L.E. & Keller, M.C. (2011) A Critical Review of the First Ten Years of Candidate Gene-by-Environment Interaction Research in Psychiatry. American Journal of Psychiatry, 168(10), 1041-1049.
  • Keller, M.C., Medland, S.E., & Duncan, L.E. (2010). Are Extended Twin Family Designs Worth the Trouble? A Comparison of the Bias, Precision, and Accuracy of Parameters Estimated in Four Twin Family Models. Behavioral Genetics, 40(3), 377-393.
  • Willcutt, E.G., Pennington, B.F., Duncan, L.E., Smith, S.S., Keenan, J.M., Wadsworth, S., DeFries, J.C., & Olson, R.K. (2010). Understanding the complex etiologies of developmental disorders: Behavioral and molecular genetic approaches. Journal of Developmental and Behavioral Pediatrics, 31(7), 533-544.
  • Duncan, L.E., Hutchison, K.E., Carey, G., & Craighead, W.E. (2009). Variation in Brain-Derived Neurotrophic Factor (BDNF) Gene is Associated with Symptoms of Depression. Journal of Affective Disorders, 115, 215-219.
  • Keller, M.C., Medland, S.E., Duncan, L.E., Hatemi, P.K., Neale, M.C., Maes, H.H., & Eaves, L.J. (2009). Modeling Extended Twin Family Data I: Description of the Cascade Model. Twin Research and Human Genetics, 12(1), 8-18.
  • Howerth, E.W., Mead, D.G., Mueller, P.O., Duncan, L., Murphy, M.D., & Stallknecht, D.E. (2006). Experimental Vesicular Stomatitis Virus Infection in Horses: Effect of Route of Inoculation and Virus Serotype. Veterinary Pathology, 43(6), 943-955.


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