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Faculty member in the Psychiatric & Neurodevelopmental Genetics Unit at Massachusetts General Hospital
Massachusetts General HospitalRichard B. Simches Research Center185 Cambridge StreetBoston, MA 02114Phone: 617-643-4371 (office), 617-724-4978 (lab)Email: email@example.com
Dr. Sahay is an Assistant Professor at the Center for Regenerative Medicine and the Department of Psychiatry at Massachusetts General Hospital, Harvard Medical School. He is also principal faculty of the Harvard Stem Cell Institute of Harvard University. The focus of Dr. Sahay’s research interests lies in understanding how stem cells in the adult brain may be harnessed to improve cognition and mood and how alterations in neural circuits contribute to the development of psychiatric disorders. The incidence and complexity of mental illnesses and cognitive impairments associated with ageing and Alzheimer’s disease underscores the need to develop novel treatments. The mission of the Sahay Lab is to generate fundamental insights into the role of adult hippocampal neurogenesis, the process by which neural stem cells generate dentate granule neurons throughout life, in hippocampal functions in encoding, memory processing and modulation of mood. By integrating cellular, circuit, systems and behavioral interrogation of adult hippocampal neurogenesis, we aspire to rejuvenate and re-engineer hippocampal circuitry to optimize circuit performance and memory processing. We predict that this strategy will impact diseases such as PTSD, Alzheimer’s disease and age-related cognitive decline.
Learn more about the Sahay Lab.
See a complete list of Dr. Sahay's publications
Lab manager Sally Levinson, BS (PhD program in Neuroscience at NYU, 2013-) Tomer Langberg, BS (2013- )
Research fellows Nannan Guo, PhD (Fudan University) Kathleen McAvoy, PhD (University of Rochester) Antoine Besnard, PhD (INSERM/CNRS/UPMC, Paris)
Graduate students Tara Raam (Program in Neuroscience) Hugo Vega-Ramirez (Program in Neuroscience)
Undergraduate students Shannen Kim (Harvard) Melissa Boldridge (Harvard) Sekinat Jumai Yusuf (Harvard)
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