Learn more about what's going on within PNGU
International research consortium addresses questions about genetic background of obsessive-compulsive disorder and Tourette syndrome
MGH investigator Dr. Jeremiah Scharf, M.D., Ph.D., lead author of a report in the October issue of the open-access journal PLOS Genetics, discusses an international research consortium's insights into the genetic architecture of obsessive-compulsive disorder, Tourette syndrome.
Genome-wide analysis of five major psychiatric disorders
PNGU faculty including Drs. Jordan Smoller, M.D., Sc.D., Phil Hyoun Lee, Ph.D., Roy Perlis, M.D., Shaun Purcell, Ph.D., and Susan Santangelo, Sc.D. were key members of a team that recently reported the largest genome-wide analysis of neuropsychiatric illness to date. The study, “Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis,” was published in The Lancet and examined genetic data from more than 60,000 people worldwide through the collaboration of the Cross-Disorder Group of the Psychiatric Genomics Consortium. The study found that common genetic variants are shared between five major psychiatric disorders: schizophrenia, bipolar disorder, major depressive disorder, attention deficit-hyperactivity disorder, and autism spectrum disorders. The study also implicated genes involved in calcium channel signaling as contributors to all five disorders, a finding that may provide biological targets for new treatment strategies for these disorders.
Mentorship award to PNGU Director
Jordan Smoller, M.D., Sc.D., PNGU director, was presented with an award for "Exceptional Mentorship in the Research Arena" by the Department of Psychiatry.
Welcome to the Genetic Code: An Overview of Basic Genetics
Wednesday, January 16, 2013
This course is offered through the Clinical Research Program on Weds. January 16 from 2-5pm in the Simches Building, 185 Cambridge Street, 3rd Floor, room 3.110 Please contact Suzanne Powell for registration details.
Grant to PNGU faculty for GWAS study of Tourette Syndrome
Dr. Jeremiah Scharf, M.D., Ph.D., PNGU faculty member and Co-Chair of the Tourette Syndrome Association International Consortium for Genetics (TSAICG) was recently awarded a $1.3 million dollar grant from the National Institute of Neurological Disorders and Stroke on behalf of the TSAICG to conduct a follow-up genome-wide association study (GWAS) in 3000 individuals with Tourette Syndrome and 3000 ancestry-matched controls. The grant will also support pilot whole exome sequencing in 150 TS parent-proband trio families to screen for rare, de novo protein-damaging mutations as a contributing factor to TS genetic susceptibility.
WCPG Travel Award to PNGU postdocs
Congratulations! The International Society of Psychiatric Genetics awarded three of its highly competitive travel awards for the XXth World Congress of Psychiatric Genetics to PNGU postdoctoral fellows: Laramie Duncan, PhD, Phil Hyoun Lee, PhD, and Nadia Solovieff, PhD.
Dr. Amar Sahay, Ph.D., was recently selected as an Ellison Medical Foundation New Scholar in Aging for his project: Reversing age related impairments in pattern separation to improve episodic memory function.
Dr. David Pauls, Ph.D., founding director of PNGU, was recently awarded the Tourette Syndrome Association's Lifetime Achievement Award "for a lifetime of commitment and research aimed at determining the genetic basis of Tourette Syndrome and related disorders."
"The Other Side of Normal"
Dr. Smoller, Director of PNGU, recently published a book entitled "The Other Side of Normal"(Harper Collins, 2012).
Mysell Award to PNGU postdoc
March 28th, 2012
Melanie Leussis, Ph.D., postdoctoral research fellow in the Petryshen lab, won the Neal Alan Mysell Award for best poster presentation by a research fellow at the Harvard Medical School Psychiatry Research Day.
Psychiatric Genetics and Translational Research Seminar
Fall 2013-Spring 2014
Please join us at our seminar. Seminars are on selected Tuesdays 10AM-11AM, Simches Building, 185 Cambridge St., Boston in the 2nd floor, Garrod and Mendel conference room. Click here for more details.