Research Centers


Smoking Cessation Program: Center for Addiction Medicine and Schizophrenia Program

At the Mass General Smoking Cessation Program, people with schizophrenia receive the best in personally tailored behavioral and medication treatment for smoking cessation as well as prevention of relapse to smoking.
  • Phone: 617-643-4691


Research from the Massachusetts General Hospital Schizophrenia Program and others has shown that, with appropriate treatment, smokers with schizophrenia can successfully quit smoking without worsening of their symptoms of schizophrenia. This work has recently been highlighted in clinical practice guidelines recommending that all people with schizophrenia spectrum disorders who smoke and want to quit be offered bupropion with or without nicotine replacement therapy along with behavioral support.

Our recent treatment study with smokers with schizophrenia or bipolar disorder here at MGH found extended duration varenicline along with behavioral support tripled cessation rates at one year for those who were able to quit for at least two weeks with varenicline and group cognitive behavioral therapy.

We offer a range of smoking cessation services, both routine and through clinical trials.

Our smoking cessation studies are not limited to patients in our psychiatric care at Massachusetts General Hospital, they are also available to the public as a health resource through our research program. Read more information about our program.

Research Projects

  • Extended duration varenicline for prevention of relapse to smoking in people with schizophrenia
  • Glycine transport inhibition for nicotine dependence in schizophrenia
  • Cooperative drug discovery for the treatment of nicotine dependence

Contact Smoking Cessation

60 Staniford St.
Boston, MA 02214

Phone: (617) 643-4691
Fax: (617) 643-1998


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