Clinical Research

Interested in research? We are always recruiting for a variety of studies! Call 617-643-2076 or (866)99-MOODS to speak with one of our clinical research coordinators.

Research Registry

To join the BCRP's Volunteer Research Registry, e-mail your contact information to BCRPnewsletter@partners.org

Current Studies MoodNetwork Do you have depression or bipolar disorder? If so, we invite you to join MoodNetwork, a new kind of study focused on collaboration between people who live with mood disorders, researchers, and clinicians. The goal of MoodNetwork is to bring together 50,000 people with mood disorders who can help change the way that depression and bipolar disorder are understood and treated today. As a member of MoodNetwork, you will have the opportunity to share your ideas and experiences with fellow participants, use online tools to track how you are feeling, and get answers to your questions about bipolar disorder and depression.

Sign up today at www.moodnetwork.org. Nutrition, Exercise, and Wellness Treatment (NEW Tx) for Bipolar Disorder NEW Tx is a study for patients with bipolar disorder (between the ages of 18-65) who are overweight and are looking to make healthier decisions in their lifestyle, specifically in the areas of nutrition, exercise, and wellness. If this applies to you, you may be eligible to participate in a research study evaluating a therapy-based health intervention for patients with bipolar disorder. In this research study, participants will receive 18 sessions of individual therapy at no cost. Brief Sleep Intervention to Reduce Suicidal Thoughts in Bipolar Disorder Do you have bipolar disorder? Are you having trouble sleeping? Have you been feeling weary of life or have thoughts of wanting to hurt yourself? If so, you may be eligible to participate in a research study to help you improve your sleep and suicidal thoughts. Patients will receive 3 sessions of therapy for bipolar disorder at no cost. Therapy Study for Sleep Problems in Bipolar Disorder Do you have bipolar disorder and trouble sleeping? If so, you may be eligible to participate in a research study evaluating a new treatment for bipolar disorder focused on improving sleep. Patients will receive 4 sessions of therapy for bipolar disorder at no cost. Our fMRI (functional Magnetic Resonance Imaging) studies Functional Magnetic Resonance Imaging (MRI) is a technique for making images of the brain. It uses magnetic fields and radio waves and is not harmful. This technique allows the investigators to evaluate changes in blood flow to various areas of the brain. Temporal Discounting Have you been diagnosed with Bipolar I/II Disorder? Have you been feeling weary of life? Are you right handed?

The Massachusetts General Hospital Bipolar Clinic and Research Program is currently enrolling for a research study examining brain functioning during a decision making task.

Eligible participants will have two study visits. The first visit will involve an interview and self-report questionnaires. The fMRI brain scan and additional interview will take place during the second visit. Participants will be reimbursed up to $100 for their time. Participants must be between the ages of 18-65.

Please contact 617-643-2076 and ask about the temporal discounting study for more information! Neural Correlates of Self-Processing The purpose of the study is to examine brain function associated with thinking about certain phrases and while making judgments about oneself. This study protocol has two parts, one psychiatric evaluation at the Massachusetts General Hospital, and one fMRI scan at MGH Imaging Center in Charlestown, MA.

If you are eligible, you will be asked to return for one MRI scan, which will take place at the MGH Imaging Center in Charlestown, MA. During the MRI scan you will be asked to complete a series of two types of tasks: One of the tasks involves simply thinking about phrases which will be presented one at a time on the screen in front of you. In the second type of task, you will be presented with personality traits on the screen in front of you, one at a time, and asked to determine whether that trait applies to you. Participants will be reimbursed up to $100 for their time.

Inclusion criteria: 18 to 64, must be right handed

Exclusion Criteria: substance abuse within the past 6 months, or if you are currently taking benzodiazepines

Multi-level Analysis for Positive Valence Systems across Mood Disorders Have you been experiencing symptoms of depression or bipolar disorder that interfere with your daily life? MGH and McLean Psychiatry researchers seek volunteers for a brain imaging study to understand how people with depression and bipolar disorder respond to reward. The study includes five sessions. If eligible to participate, you can receive up to $352.25.

We are seeking right-handed individuals, 18-65 years old with no serious medical or neurological illness other than depression or bipolar disorder to participate in 5 study sessions, each lasting between 2-3.5 hours. Research Registry To join the BCRP’s Volunteer Research Registry, e-mail your contact information (phone number, e-mail address, address, birth date) to BCRPnewsletter@partners.org. This will allow us to contact you in the future should a study begin that may be beneficial for you.