Clinical Research

CES Study: The purpose of this study is to see if using Cranial Electrical Stimulation (CES) helps improve the symptoms of major depressive disorder (MDD) in people taking an antidepressant that is not working for them.

Are you taking an antidepressant but still feeling sad or depressed?

Are you interested in novel treatments for your depression?

If so, you may be eligible to participate in a research study using cranial electrical stimulation (CES) to treat depression being conducted at Massachusetts General Hospital. CES involves a small electrical pulse traveling over your scalp and is safe and painless. This treatment is not the same as electroconvulsive therapy (ECT).

We are studying the device’s effectiveness in treating depression, as well as its safety. Treatment visits will take place once a week for 3 weeks. On the days that you do not come in to our clinic you will administer the CES treatment to yourself at home. We will give you a CES device to borrow for the duration of the study. We can validate your parking ticket if you park in a hospital garage. We will also pay you $50 for every week that you successfully complete the treatment as well as an additional $50 for returning the device to us upon completion of the study.

If you complete the entire study, you may choose to have active CES treatment up to 20 minutes a day every weekday for 3 weeks after the end of the study.

For more information, please contact Clair at 617-724-3673 or ccassiello@partners.org