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- MGH/BWH
study identifies Alzheimer's associated changes in the eye
Research team led by investigators from the MGH and BWH has discovered
that amyloid-beta (A-beta), the protein that forms plaques in the brains
of people with Alzheimer's disease, also can be detected in the lens
of the human eye. The investigators were able to identify A-beta in
lens samples from elderly individuals with and without the disorder.
An unusual pattern of amyloid deposits, however, was found only on the
lenses of Alzheimer's patients. The observation, published in the April
12 issue of The Lancet, could lead to the development of a non-invasive
test to diagnose and track the development of the devastating brain
disorder.
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